女性不孕症垂体腺瘤的治疗与结果

Result of treatment and outcome of infertile women with pituitary adenoma

作者报告４５例女性不孕症垂体腺瘤的治疗结果，术后３４例（７５．６％）生育，其中１０例单纯手术，２４例辅加涅隐亭治疗，１１例（２４．４％）仍不育。结果显示，手术前后血清泌乳素（ＰＲＬ）水平低者及微小腺瘤患者生育率较高，反之则低，术后持续有高泌乳素血症者，多需辅加药物治疗。残瘤较大者妊娠期有视路受损的危险性，应在肿瘤获得充分治疗后怀孕，且应定期随诊，严密观察视力、视野。

Result of treatment and outcome of 45 infertile women with pituitary adenomas were reoorted.Thirty-four cases(75.6%)became pregnant after treatment 10 cases by surgery only and 24 cases by surgeryplus administration of bromocriptine.The chance rates for pregnancy in patients with lower prolactin levelsand micro-or srnall(<20 mm)adenomas were significantly higher than those with higher prolactin levels andmacroadenomas(>20 mm).Most of patients with hyperprolactinemia after operation required medical treat-ment.There is a risk of functional impairment of optic nerves during pregnancy for the patients with a largeremain tumor.Such patients should be monitored during pregnancy by measurement of prolactin levels and vi-sual field examination at monthly intervals.