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Update on the laboratory diagnosis and monitoring of HIV infection

Update on the laboratory diagnosis and monitoring of HIV infection
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摘要 In China, the estimated number of HIV infected cases is approaching one million. Although public education has been initiated for awareness and behavioral modification for this devastating infection, better diagnostic methods are needed to identify infected persons and manage infection. Simple and more accurate diagnostic tools have become available, particularly for early detection and to monitor treatment in those who receive anti-retroviral treatment. In this short review, we summarize some of the common and new methodologies that can be used in clinical laboratories, in the field, or in private laboratories. These range from simple antibody tests to more sophistical methods that are used to monitor disease progression and identify drug resistance. These tools can assist physicians, medical practitioners, and laboratory personnel to select suitable diagnostic tools for the diagnosis, blood screening, monitoring of disease progression, and for detection of drug resistance to anti-retroviral therapies. In China, the estimated number of HIV infected cases is approaching one million. Although public education has been initiated for awareness and behavioral modification for this devastating infection, better diagnostic methods are needed to identify infected persons and manage infection. Simple and more accurate diagnostic tools have become available, particularly for early detection and to monitor treatment in those who receive anti-retroviral treatment. In this short review, we summarize some of the common and new methodologies that can be used in clinical laboratories, in the field, or in private laboratories. These range from simple antibody tests to more sophistical methods that are used to monitor disease progression and identify drug resistance. These tools can assist physicians, medical practitioners, and laboratory personnel to select suitable diagnostic tools for the diagnosis, blood screening, monitoring of disease progression, and for detection of drug resistance to anti-retroviral therapies.
出处 《Cell Research》 SCIE CAS CSCD 2005年第11期870-876,共7页 细胞研究(英文版)
关键词 爱滋病病毒 病毒感染 实验室诊断 实验室监控 疾病传染 HIV, diagnosis, viral load, drug resistance
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  • 1Constantine NT, ed. Retroviral Testing and Quality Assurance:Essentials for Laboratory Diagnosis. Ann Arbor, MI: Malloy Publishers, 2005.
  • 2Branson BM. FDA approves OraQuick for use in saliva. On March 25, the FDA approved the first rapid test for HIV in oral fluids. AIDS Clin Care 2004; 16:39.
  • 3Update CHATPN. Uncommon HIV- 1 Virus Detected in China.Kyodo News Services. 2000.
  • 4Bulterys M, Jamieson DJ, O'Sullivan MJ, et al. Rapid HIV-1 testing during labor: a multicenter study. JAMA 2004; 292:219-23.
  • 5Prevention CfDCa. CDC: better needlestick reporting required.AIDS Alert 1997; 30-1.
  • 6Constantine NT, Ketema F. Rapid confirmation of HIV infection.Int J Infect Dis 2002; 6:170-7.
  • 7Constantine NT, Sill AIM, Jack N, et al. Improved classification of recent HIV- 1 infection by employing a two-stage sensitive/less-sensitive test strategy. J AIDS 2003; 32:94-103.
  • 8Albrecht H, Hoffmann C, Degen O, et al. Highly active antiretroviral therapy significantly improves the prognosis of patients with HIV-associated progressive multifocal leukoencephalopathy. AIDS 1998:12:1149-54.
  • 9de Mendoza C, Soriano V, Perez-Olmeda M, et al. Different outcomes in patients achieving complete or partial viral load suppression on antiretroviral therapy. J Hum Virol 1999; 2:344-9.
  • 10Guatelli JC, Whitfield KM, Kwoh DY, Barringer KJ, Richman DD, Gingeras TR. Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication. Proc Natl Acad Sci U S A. 1990; 87:1874-8.

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