氨基磺酸催化合成环己酮1,2-丙二醇缩酮

Synthesis of cyclohexanone 1,2-propanediol ketal with aminosulfonic acid as catalyst

以氨基磺酸为催化剂,对以环己酮和1,2-丙二醇为原料合成环己酮1,2-丙二醇缩酮进行了研究。较系统地研究了酮醇摩尔比,催化剂用量,反应时间诸因素对收率的影响。最佳反应条件为:n(酮)∶n(醇)=1∶1.5,催化剂用量为1 g,带水剂环己烷15 mL,反应时间60 m in。上述条件下,环己酮1,2-丙二醇缩酮的收率可达71.15%。

cyclohexanone 1,2-propanediol ketal （ Ⅰ ）was synthesized from cyclohexanone （ Ⅱ ） and 1,2- propanediol（ Ⅲ ） in the presence of aminosulfonic acid （ Ⅳ ）. Factors influencing the product yield were discussed and the best reaction conditions were found. Experimental result showed that Ⅳ is an excellent catalyst . With n（ Ⅱ ） ： n（ Ⅲ ）=1 ： 1.5,w（Ⅳ ）=1 g,the carrying water reagent is 15 mL,and the reaction time=60min,yieldof I can reach 71.15%.