呼吸机相关肺炎的病原菌分析

Pathogen analysis of ventilator-associated pneumonia

目的通过对83例危重病患者呼吸机相关性肺炎的病原体及药敏试验分析,指导临床药物治 疗,避免一些不良因素的存在。方法对83例各种危重病持续机械通气患者痰培养病原体检出结果进行 分析。结果呼吸机相关肺炎中,金黄色葡萄球菌检出率最高,对去甲万古霉素及丁胺卡那霉素敏感性 高,而对头孢噻肟钠、舒氨西林等耐药;其次检出率较高的为费劳地枸橼酸杆菌,对泰能和舒普深等敏 感,而对左氧氟沙星及阿莫西林等耐药。结论合理应用抗生素,避免院内感染的危险因素,提高患者 的治愈率。

Objective To instruct clinical treatment and avoid bad factors of ventilator-associated pneumonia through analysis of the pathogens and drug sensitive tests in 83 cases of dying and severely ill patients suffering from ventilator-associated pneumonia. Methods Pathogens detected from sputum cultures of 83 patients with lasting mechanical ventilation were analyzed. Results Staphylococcus aureus was the most common pathogen detected from ventilator-associated pneumonia, and had high sensitivity to norvancomycin and amikacin, but was resistant to cefotaxime and sultamicillin. The second commonest pathogen detected was Feilodi which was sensitive to tienam and cefoperalone-sulbactam but resistant to levofloxacin and amoxicillin. Conclusion Rational use of antibiotics and avoidance of cross infection in hospital can improve the curative rate of ventilator-associated pneumonia patients.