CT对肾上腺增生性疾病诊断价值的研究

Study on the value of CT in diagnosis of adrenal gland hyperplastic diseases

目的探究CT对肾上腺增生性疾病的诊断价值。方法对CT发现的肾上腺增生病例测血皮质 醇(8:00、16:00、0:00)及隔夜1、8 mg地塞米松抑制试验,测定血管紧张素及醛固酮(基础、激发)、24h VMA及有关生化指标,同时进行肾上腺B超检查。结果111例中有23例为库兴氏综合征,3例为原发性 醛固酮增多症,其余85例为无激素分泌功能的肾上腺增生性疾病。B超与CT相比对肾上腺增生性疾病 的检出率有显著性差异(P<0．001)。结论CT是发现和诊断肾上腺增生性疾病的有效检查方法。

Objective To investigate the value of CT in diagnosis of adrenal gland hyperplastic diseases. Methods Serum cortisol at 8：00, 16：00 and 0：00 o＇clock, 1 mg and 8 mg dexamethasone suppression test of the previous night, angiotensin, aldosterone（basal, excited）, 24 h VMA and other related biochemical indexes were detected in patients with adrenal gland hyperplastic diseases diagnosed by CT. Ultrasonic examination of adrenal gland was also performed simultaneously. Results Out of 111 patients, 23 had Cushing＇s syndrome, 3 had primary aldosteronism and 85 had adrenal gland hyperplastic diseases without secreted hormones. There was significant difference between CT and brightness mode ultrasonic examination in diagnosis of adrenal gland hyperplastic diseases（P 〈 0.001）. Conclusion CT is effective in detection and diagnosis of adrenal gland hyperplastic diseases.