板蓝根提取物化学成分研究(Ⅰ)

The chemical constituents from Isatis indigotica Fort.(I)

利用反复硅胶柱色谱对板蓝根中的化学成分进行分离纯化,共得到7个化合物,分别鉴定为:腺苷(adenosine,1)、棕榈酸(2)、棕榈酸α,α′-双甘油酯(3)、棕榈酸-单甘油酯(4)、青黛酮(qingdainone,5)、靛玉红(indirubin,6)、β-谷甾醇(7)。其中化合物3、4为首次从该属中分离得到。

The chemical constituents of the extract from the leaves of Isatis indigotica Fort.. were isolated by repeat silica gel column chromatography. Physical-chemical characters and spectroscopic analysis were employed for the structural identification. Compounds 1 -7 were elucidated as adenosine（1）, plamitic acid （2）, plamitic acid α, α ＇-dipropyl ester（3）, plamitic acid α-propyl ester（4）, qingdainone（5）, indirubin（6）and β-sitosterol（7）. Among them, compound 3, 4 are isolated from Isatis indigotica Fort. for the first time.