儿童1型糖尿病90例

Clinical Analysis of 90 Children with Type 1 Diabetes Mellitus

目的探讨儿童1型糖尿病(IDDM)的发病情况、临床特点、远期并发症及酮症酸中毒(DKA)的治疗。方法回顾性分析1993～2003年我院90例IDDM患儿的发病情况,临床特点,远期并发症,并探讨DKA的治疗。结果10～16岁儿童发病率最高,感染是诱发DKA的常见原因,未长期坚持胰岛素治疗易导致IDDM远期并发症的发生。结论小剂量胰岛素持续静滴、纠正水电解质紊乱、调节酸碱平衡是抢救DKA的关键;坚持长期胰岛素治疗是防治远期并发症IDDM的关键。

Objective To analyze the incidence, clinical feature and late complications, and treatment for diabetes ketoacidosis （DKA） in children with type 1 diabetes rnellitus. Methods Ninty children with type 1 diabetes mellitus within 10 years were retro- spectively reviewed. The onset sinmtion, clinical feature and long- term complication, and treatment of DKA were analized. Results High morbidity was found in 10 to 16 years old children. DKA was often caused by infection; late cornplications of diabetes mellitus was resulted from interrupted injection of insulin. Conclusions Emergency treatment for DKA may involve the injection of small dose insulin,correction of the disorder of water and electrolysis and regulation of acid - base. The education of patients and parents about diabetes mellitus and long- term injection of insulin are of importance in preventing the complications.