单光子发射计算机断层显像对新生儿甲状腺功能减低的诊断价值

Value of Single Photon Emission Computed Tomography Thyroid Imaging for Diagnosis of Congenital Hypothyroidism

目的采用甲状腺单光子发射计算机断层显像(SPECT)探讨其对新生儿先天性甲状腺功能减低(甲低)的诊断价值。方法对经新生儿疾病筛查发现的19例甲低患儿,静脉注射99mTcO418.5～37.0MBq,15min后行甲状腺显像。结果甲状腺SPECT基本正常5例,单纯性肿大1例,肿大且放射性分布增加2例,异位、缺如各4例,显影不清3例。结论甲状腺SPECT对甲低原因如甲状腺发育不全、缺如和异位等可做出满意的判断,结合甲状腺显像和血清T3、T4、TSH检查,对新生儿甲低诊断具有重要意义。

Objective To explore the causes of congenital hypothyroidism by single photon emission computed tomography （SPECT） thyroid imaging. Methods Nineteen cases with congenital hypothyroidism were collected,and SPECT thyroid imaging was performed 15 minutes lale after injecled ^99mTcO4^- 18.5 - 37.0 Mlkl. Results Five cases were found with normal glands, 1 case with enlarged thyroid, 2 cams with enlarged thyroid and increased radiation,4 cases with ectopic thyroid,4 with a hypogenetic thyroid,and the last 3 cases showed no thyroid imaging. Conclusions The causes of congenital hypothyroidism can be found by SPECT thyroid imaging,which is important to the diagncxsis of congenital hypothyroidism combined with detection of T3 ,T4 ,TSH.