不稳定型心绞痛患者的血管内超声分析

Analysis of intravascular ultrasound in the patients with unstable angina pectoris

目的:应用血管内超声(IVUS)探讨不稳定型心绞痛(UAP)患者的斑块形态学特点。方法:经冠状动脉造影和IVUS检查的冠心病患者57例,其中稳定型心绞痛(SAP)21例,UAP 36例,根据斑块回声的强度,将斑块分为软斑块、纤维斑块、钙化斑块、混合斑块和斑块破裂等,分析比较UAP和SAP患者的斑块的形态学特点。结果:IVUS发现软斑块的比例在SAP和UAP患者中分别为47.6%和75.0%,纤维斑块的比例分别为52.4%和25.0%,斑块破裂分别为0和30.6%,钙化斑块分别为52.4%和19.4%(均P<0.05)。结论:IVUS显示UAP的斑块形态学特点主要表现为软斑块和斑块破裂。

Objective：To investigate the characters of plaque morphology of the patients with unstable angina pectoris （UAP） byintravascular ultrasound（IVUS）. Method： Between Jul 2001 and-Nov 2002,57 patients with coronary artery disease （CAD）, 21 with stable angina pectoris, 36 with UAP, All the patients underwent coro nary angiography（CAG） and IVUS of culprit vessel. According to the intensity of plaque echo, lesion was identified as soft plaque, fibrous plaque, calcified plaque, mixed plaque and plaque rupture etc, we analyzed and corn pared the characters of plaque morphology hetween the patients with UAP and SAP. Result： IVUS showed the percentage of soft plaque was 41% and 79% respectively in SAP group and UAP group （ P〈 0.05）, 25% and 53% in fibrous plaque （ P〈0.05） , 0 and 33% in plaque rupture （ P〈0.05）, 42%and 14% in calcified plaque （ P 〈0. 05）. Conclusion：IVUS revealed the characters of plaque morphology in the patients with UAP were mostly soft plaque and plaque rupture.