可溶性细胞间黏附分子与胆汁淤积被引量：1

Intercellular adhersion molecule with cholestasis

下载PDF

导出

摘要可溶性细胞间黏附分子_1(sICAM_1)在胆汁淤积性黄疸发生发展中具有重要作用,胆汁中sICAM_1水平表达程度能反映肝细胞损伤程度及预后。本文就其在胆汁淤积病理过程中的作用及意义加以综述。

作者刘凡黄志华

机构地区华中科技大学同济医学院附属同济医院儿科

出处《国外医学（流行病学．传染病学分册）》 2005年第6期380-381,共2页 Epidemiology Lemology Foreign Medical Sciences

关键词细胞黏附分子-1 胆汁淤积

分类号 R575.2 [医药卫生—消化系统]

引文网络
相关文献

参考文献9

1Ohtsuka M,Miyazaki M,Kubosawa H,et al.Role of neutrophils in sinusoidal endothelial cell injury after extensive hepatectomy in cholestatic rats.J Gastroenterol Hepatol,2000,15(8):880-886.
2Essani NA,Fisher MA,Farhood A,et al.Cytokine-induced upregulation of hepatic intercellular adhesion molecule-1 messenger RNA expression and its role in the pathophysiology of murine endotoxin shock and acute liver failure.Hepatology,1995,21 (6):1632-1639.
3Koeppel TA,Trauner M,Baas JC,et al.Extrahepatic Biliary obstruction impairs microvascular perfusion and increasesleukocyte adhesion in rat liver.Hepatology,1997,26(5):1085-1091.
4KobayashiA,ImamuraH,IsobeM,etal.Mac-1(CD11b/CD18)and in-tercellular adhesion molecule-1 in ischemiareperfusion injury of rat liver.Am J Physiol Gastrointest Liver Physiol,2001,281(2):G577-G585.
5Polzien F,Ramadori G.Increased intercellular adhesion molecule-1 serum concentration in cholestasis.J Hepatol,1996,25(6):877-886.
6Bloom S,Fleming K,Chapman R,et al.Adhesion molecule expression in primary sclerosing cholangitis and primary biliary cirrhosis.Gut,1995,36(4):604-609.
7Minnick KE,Kreisbery R,Dillon PW.Soluble ICAM-1(s ICAM-1)in biliary atresia and its relationship to disease activity.J Sury Res,1998,76(1):53-56.
8Broome U,Nemeth A,Hultcrantz R,et al.Different expression of HLA-DR and ICAM-1 in livers from patients with biliary atresia and Byler' s disease.J Hepatol,1997,26(4):857-862.
9Gulubova MV.Intercellular adhesion molecules-1 ( ICAM-1 )expression in the liver of patients with extrahepatic cholestasis.Acta Histochem,1998,100(1):59-74.

同被引文献10

1侯振江,牟召新.细胞间黏附分子及其在肝脏病诊疗中的应用[J].医学综述,2004,10(8):480-482. 被引量：3
2庄明明,问奕欣,洪晓鹏,郑卫军.肝硬化患者治疗前后可溶性细胞间黏附分子-1水平变化及其临床意义[J].国外医学（放射医学核医学分册）,2005,29(3):118-120. 被引量：2
3Samransarnruajkit R, Prapphal N, Deelodegenavong J, et al. Plasma soluble intercellular adhesion molecule-1 (slCAM-1) in pediatric AR138 during high frequency oscillatory ventilation: A predictor of mortality[J]. Asian Pac J Allergy Immunol,2005,23(4) : 181 - 188.
4Hillstron J, Duane WC, Eekfeldt JH, et al. Lack of benefit of ursodeoxyeholie acid in drug- induced eholestasis in the rat [ J ]. Proc Soc Exp Biol Med,1992,200(1):122-126.
5Wu et Davis PA, Luketie VA, et al. A review of the physiological and irnmunologieal functions of biliary epithelial cells: Targets for primary biliary cirrhosis, primary sclerosing eholangitis and drug - induced duetopenias[ J ]. Clin Dev Immunol,2004,11 (3 - 4) :205 - 213.
6Bostantjopoulou S, Katsarou Z, Frangia T, et al. Endothelial function markers in parkinsonian patients with hyperhomocysteinemia [ J ]. J Clin Neurosci,2005,12(6):669-672.
7Zajkowska J M, lzycka A, Jablonska E, et al. Serum and cerebrospinal concentrations of sICAM- 1, sICAM - 2, sICAM - 3 in neuroborreliosis and tick borne encephalitis preliminary report [ J ]. Pol Merkuriusz Lek, 2005,19(110) : 152 - 157.
8EI- Gohary AM, Fawaz NA, Hassoba HM, et al. Soluble ICAM-1 in patients with chronic hepatitis C infection:A prognostic marker of disease aetivity[J]. Egypt J Immunol, 2004 ,11( 2 ) :109 - 119.
9Polzien F, Ramadori G. Increased intercellular adhesion molecule-1 serum concentration in cholestasis [ J ]. J Hepatol, 1996, 25 ( 6 ) :877 - 886.
10Kossor DC, Meunier PC, Handler JA, et al. Temporal relationship of changes in hepatobiliary function and morphology in rats following alpha- naphthylisothiocyanate ( ANIT ) administration [ J ]. Toxicol Appl Pharmacol, 1993,119( 1 ) : 108 - 114.