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角质细胞生长因子在妇产科的研究进展 被引量:3

Progress in research on keratinocyte growth factor in gynecology and obstetrics
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摘要 角质细胞生长因子由成纤维细胞及其他间质细胞分泌,是成纤维细胞生长因子家族的成员。角质细胞生长因子能特异性刺激上皮细胞有丝分裂,调节间质-上皮相互作用,有广泛的生物学功能。该文就角质细胞生长因子在妇产科的研究进展进行综述。 Keratinocyte growth factor is secreted by fibroblast and mesenchymal cells, and is a member of fibroblast growth factor family. KGF can specifically stimulate the epithelial mitogenesis and regulate the interaction of mesenchyma and epithelia, so it has broad biological functions. In this review, we summarized progress in research on KGF in gynecology and obstetrics.
作者 谯利 其木格
出处 《国外医学(妇幼保健分册)》 2005年第6期398-400,共3页 Foreign Medical Sciences (Section of Maternal and Child Health)
关键词 角质细胞生长因子 卵泡 子宫内膜 keratinocyte growth factor(KGF) follicle endometrium
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参考文献18

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同被引文献21

  • 1王秀梅,黎莉,郝静,张芳,王妍,刘友德.KGF在乳腺癌的表达与临床意义[J].中国现代普通外科进展,2006,9(1):37-39. 被引量:2
  • 2李小利,李保应,高海青,郭瑞臣,王本杰.角质细胞生长因子抗大鼠肝纤维化的实验研究[J].中华消化杂志,2006,26(3):193-194. 被引量:3
  • 3陆琳,胡丽娜,李双庆,贾海军,李金科,王登凤.角质细胞生长因子及其受体在Hela细胞中的表达及其作用[J].四川大学学报(医学版),2007,38(3):437-439. 被引量:6
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  • 5Yoshino M, Ishiwata T, Watanabe M, et al.Keratinocyte growth factor receptor expression in normal colorectal epithefial cells and differentiated type of colorectal cancer[ J]. Oncol Rep,2005,13 (2) : 247 -252.
  • 6Zang X P, Siwak D R, Nguyen T X. KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1, 2 [ J ]. Clin Exp Metastasis ,2004,21 ( 5 ) :437-443.
  • 7Movassat J, Beattie G M, Lopez A D. Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells[ J]. Diabetologia,2003,46(6) :822-829.
  • 8Ulrich K, Stem M, Goddard M E, et al. Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury[J].Am J Physiol Lung Cell Mol Physiol,2005,288 (6) :L1179-L1192.
  • 9Spielberger R, Stiff P, Bensinger W, et al. Palifermin for oral mucositis after intensive therapy for hEMsatologic cancers [ J ]. N Engl J Med, 2004,351 ( 25 ) :2590-2598.
  • 10Frank B,Michael V,Sylvin C,et al.Ras p21 expression in the progression of breast cancer[J].Hum Path,1987,1268-1275.

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