慢性咳嗽病因诊断探讨

Etiological Diagnosis of Chronic Cough

目的:探讨慢性咳嗽的病因。方法:采用慢性咳嗽解剖学诊断程序,对96例持续咳嗽8周以上的患者进行病因初步诊断,并通过针对性治疗证实。结果:在96例慢性咳嗽患者中,96.9%(93/96)的病因得到明确,其中鼻后滴漏综合征(postnasal drip syndrom e,PNDS)46.9%(45/96),咳嗽变异型哮喘(cough variant asthm a,CVA)42.7%(41/96),胃食管反流性疾病(gastroesophageal reflux d isease,GERD)7.3%(7/96),病因未明3.1%(3/96)。针对病因特异性治疗,96.9%(93/96)患者的咳嗽症状消失或显著改善。结论:PNDS、CVA是慢性咳嗽的常见原因;试验性病因治疗有效是确诊病因的重要环节。

Objective： To investigate the cause of chronic cough. Methods： The causes of 96 patients with consecutive cough for more than eight weeks were primarily evaluated with an anatomic diagnostic protocol and then determined by the specific therapy. Results ： The causes of cough was determined in 93 of 96 （96.9%） patients. Cough was due to postnasal drip syndrome in 45 （46.9%） patients, cough variant asthma in 41 （42.7%） patients, gastroesophageal reflux disease in 7 （7.3 % ）patients. After active management based on the diagonosis,cough improved in 93 patients（96.9% ）. Conclusions： PNDS and CVA were important causes of chronic cough. A positive response to the specitic theraphy was essential to a definite diagnosis.