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二氢嘧啶脱氢酶基因多态性研究的现状与进展

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作者 贾莉 蔡剑平 郭健
机构地区 北京医院卫生部临床检验中心
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2005年第12期1313-1315,共3页 Chinese Journal of Laboratory Medicine
基金 卫生部北京医院重点科研资助项目(200208)
关键词 5-氟尿嘧啶 代谢酶基因 多态性研究 药物代谢酶 肿瘤治疗 相关基因 20世纪 指导作用 疗效观察 二氢嘧啶脱氢酶
分类号 R96 [医药卫生—药理学]
  • 相关文献

参考文献27

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二级参考文献14

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  • 4Wei X, McLeod HL, McMurrough J,et al. Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity[J].J Clin Invest, 1996,98:610-615.
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  • 7Vreken P,Van Kuilenburg ABP,Meinsma R,et al. Identification of a four-base deletion (del TCAT296-299) in the dihydropyrimidine dehydrogenase gene with variable clinical expression[J].Hum Genet, 1997,100: 263-265.
  • 8Wei X, Elizondo G, Sapone A,et al. Characterization of the human dihydropyrimidine dehydrogenase gene[J]. Genomics,1998,51: 391-400.
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中华检验医学杂志
2005年 第12期

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