胚胎停育相关因素研究

Astudy on the coorelated factors of the emtryo damage

目的探讨胚胎停育的原因。方法对115例有胚胎停史患者询问病史(询问有无有害物质接触史、家族史)进行妇检、盆腔B超、感染因素的检查(支原体、衣原体、弓形虫、风疹、巨细胞病毒(、游离T3、T4、空腹血糖、患者丈夫进行精液常规检查,患者夫妇同时检查染色体核型、ABO血型及血清IgG抗体滴度水平检测。结果在病因明确的胚胎停育中感染因素中支原体、衣原体感染占首位(22.61%),其次是染色体异常(10.43%)、ABO血型不合(6.96%)、其他因素(8.70%),不明原因占50.43%。结论对胚胎停育夫妇应进行系列检查,尽可能确定病因学诊断,以免漏诊,同时也有利于早期针对部分病因进行处理,减少自然流产的发生率。

Objective：To total of 115 cases with embryo damage recently were carefully reviewed （include the histories of contacted the noxious substance and family histories）. All of those patients were taken pelvic examinations, pelvic ultrasound test, the test for the infections of UU, CT RV, TOX and CMV, free 13 and T4, blood - fasting sugar, the routine sperm tests for their husbands, the tests of the chromosome types, ABO blood types and the title of serum IgG antibodies of all couples. Results ： In all those with clear etiopathogenisis, CT and UU infections were the most common factors （22.61% ）. Then that were the chromosome abnormality （10.43 % ）, ABO blood incompatibla （6.96%）, the others （8.70%） and the unknowns were 50.43% .Conclusions：It is important to make a series of tests for the couple with embryo damage to find the efiopathogenisis and avoid missed diagnosis, in order to give them early treatment pointed to their etiopathogenisis and decrease the rate of spontaneous abortion.