摘要
目的:探讨济南市汉族育龄妇女多囊卵巢综合征(PCOS)患病状况及其临床特点。方法:以2003年ESHRE/ASRM建议诊断标准,按流行病学整群抽样方法调查济南市1027例育龄妇女中PCOS的患病状况。结果:(1)以ESHRE/ASRM 3条指标符合2条的原则检出PCOS 85例,群体患病率为6.46%;(2)检出的PCOS中稀发排卵、多囊样卵巢(PCO)、高睾酮(T)血症、临床高雄(F-G≥6多毛和痤疮)分别占89.4%、72.94%、57.65%、38.8%(1.18%和38.8%);每两项指标组合:稀发排卵+PCO、稀发排卵+高T、PCO+高T分别占60%、45.9%、38.8%;符合3条指标而临床、生化高雄仅有其一者占48.2%,两者均有占11.8%;不孕占7.06%、肥胖占8.23%。按汉族妇女F-G≥2分标准,群体PCOS中多毛率为37.65%。结论:(1)PCOS占济南市汉族育龄妇女的6.46%。(2)ESHRE/ASRM标准总体上是适合济南汉族育龄妇女PCOS检出的标准,多项指标可提高检出的特异度;(3)多毛作为临床高雄指标F-G≥2分更适于汉族人群。
Objective :To explore the prevalence and characters of the polycystic ovary syndrome (PCOS) in general population of Han ethnic in Jinan city. Method:With cluster sampling epidemic method, 1027 women from Jinan city were investigated by ESHRE/ASRM criteria. Results: (1) According to the ESHRE/ASRM diagnostic criteria,85 PCOS patients were diagnosed, the prevalence of PCOS in general Han population in Jinan city was accounted for 6.46%. (2) Among all PCOS patients, rates of Oligo-ovulation, PCO, biochemical and clinical of androgen excess signs were 89.4% ,72.94% ,57.65% and 38.8% ( 1.18% hirsutism by F-G≥6 and 38.8% acne)respectively; 60% was Oligo-ovulation with PCO,45.9% was Oligo-ovulation with biochemical hyperandrogenism and 38.8% was PCO with biochemical hyperandrogenism; 48.2% and 11.8% patients meet 3 criteria with one / both of androgen excess signs (clinical / biochemical ) ; infertility and obesity were accounted for 7.06% and 8.23%. By our investigated F-G score ≥2 score standard,hirsutism was account for 37.65% in PCOS patients from general population. Conclusions: ( 1 ) The prevalence of the PCOS in general Han ethnic women population in Jinan city is accounted for 6.46%. (2) Generally, ES- HRE/ASRM criteria is the suitable standard for Chinese PCOS diagnosis. (3) This investiga- tion suggested that F-G score ≥2 score as cirteria of hirsutism may be more suitable for Chinese Han population.
出处
《现代妇产科进展》
CSCD
北大核心
2005年第6期442-444,共3页
Progress in Obstetrics and Gynecology