血管缝合器在经股动脉冠状动脉介入治疗后的临床应用

Clinical use of a suture-mediated closure device after percutaneous coronary intervention

目的:评价血管缝合器Angio-seal缝合冠状动脉介入治疗术(PCI)股动脉的效果。方法:选择我院PCI病人61 例,平均年龄(67．4±11．5)岁,随机分为应用血管缝合器组30例,手法压迫组(人工压迫、绷带加压包扎)31例。比较两 组病人的平均止血时间、卧床时间、住院时间,局部血管的并发症。结果:血管缝合器组与手法压迫组平均止血时间分 别为(5．7±3．4)min,(24．9±5．6)min;平均卧床时间分别为(4．3±1．0)h,(23．8±2．1)h(P均<0．01);平均住院 天数分别为(10±3)d．(15±4)d(P<0．05);穿刺部位并发症例数分别为1例(3．3％),7例(22．6％),P<0．01。结 论:血管缝合器缝合冠状动脉介入术后全身肝素化的血管穿刺部位,效果理想,值得推广。

Objective ： To assess the safety and efficacy of a suture-mediated closure device Angio-seal applied to femoral arterial puncture site after pereutaneous coronary intervention （PCI）. Methods： A total of 61 patients were included Emean age （67.4± 11.5） years] and randomly divided into suture-mediated closure device group （n= 30） and manual compression group （n=31）. The time of hemostasis, day lying in bed and in hospital, complication were observed. Results： The time of hcmostasis [ （5.7±3.4） min], day lying in bed [ （4.3±1.0） h] decreased （P〈0.01 all）, day in hospital [ （10±3） d] decreased （P〈0.05）, complication （3.3%） decreased （P〈0.01） in the suture-mediated closure group compared with manual compression group [ （24.9 ± 5.6） min, （23.8 ± 2.1 ） h, （ 15 ± 4） d, 22.6 % respectively]. Conclusion： The use of a suture-mediated closure device is a safe alternative to manual compression.