经前期综合征肝气郁证猕猴模型评价指标

Evaluation for Indexes of Rhesus Monkey Model of Stagnation of Liver-Qi of Premenstrual Syndrome

目的:探索经前期综合征(PMS)肝气郁证猕猴模型评价指标。方法:拟定复制肝气郁证猕猴模型的造模方法进行试验。模型评价指标采用表情行为定性与血清单胺类神经递质水平毛细管电泳检测。结果:模型具有稳定性和重现性,受试猕猴月经前呈现近似该病证的临床表现,血清中单胺类神经递质含量发生变化。结论:借助《雌性实验猕猴情绪评价量表》,确立 PMS肝气郁证猕猴模型宏观、微观评价指标。

Objective：To probe into indexes of evaluating rhesus monkey model of stagnation of liver-Qi of prementrual syndrome （PMS）. Methods：Rhesus monkey model of stagnation of liver-Qi of premenstrual syndrome was developed and qualitative analysis of expression and behaviors, and serum monoaminergic neurotransmitters examined with capillary electrophoresis were used as indexes of evaluating the model. Results：The model had stability and reiteration. Rhesus monkey in premenstrual phase showed similar clinical manifestions of this disease, with serum level of monoaminergic neurotransmitters changed. Conclusion： Macroscopic and microscopic indexes for evaluating rhesus monkey model of stagnation of liver-Qi of premenstrual syndrome can be established by means of Emotion Scale of Female Experimental Rhesus Monkey.