毛草龙化学成分的研究

Studies on the chemical constituents in herb of Ludwigia octovalvis

目的:研究毛草龙的化学成分.方法:用色谱法和波谱法对毛草龙的化学成分进行分离和结构鉴定.新鲜全草95%乙醇提取物依次用环己烷、醋酸乙酯和正丁醇萃取,用硅胶等柱色谱分离.结果:从毛草龙全草中分离、鉴定了13个化合物:β-谷甾醇(1),齐墩果酸(2),2α-羟基熊果酸(3),委陵菜酸(4),胡萝卜苷(5),麦芽酚(6),木犀草素(7),槲皮素(8),芹菜素(9),短叶苏木酚酸甲酯(10),没食子酸(11),3,4,8,9,10-五羟基二苯并[b,d]吡喃-6-酮(12)和鞣花酸(13).结论:化合物3,4,6～13均为首次从该植物分离得到,化合物3,4,6,10,12均为首次从该属植物分离得到.

Objective： To study the chemical constituents of the herb of Ludwigia ocovalvis. Method： Chemical constituents were isolated by the repeated silica gel column chromatography, and their structures were elucidated by the physicochemical properties and spectral analysis. Result： Thirteen compounds were obtained and determined as follows： β-sitosterol （ 1 ）, oleanolic acid （2）, 2α-hydroxy ursolic acid （3）, tormentic acid （4）, daucosterol （5）, maltol （6）, luteolin （7）, quercetin （8）, apigenin （9）, methyl brevifolincarboxylate （10）, gallic acid （11）, 3, 4, 8, 9, 10-pentahydroxydibenzo[b, d]pyran-6-one （12）, and ellagic acid （13）. Coneluslon： Compounds 3, 4, 6-13 were isolated from the plant for the first time. And compounds 3, 4, 6, 10, 12 were obtained from the genus for the first time.