胰岛素泵在糖尿病患者手术前的应用

Application of Insulin Pump in Preoperative Diabetic Patients

目的:了解胰岛素泵在糖尿病患者手术前使用的价值。方法:106例糖尿病患者,术前随机分配成两组:胰岛素泵持续皮下注射胰岛素(CSⅡ)组与每日多次皮下注射胰岛素(M SⅡ)组,CSⅡ组采用美国M in iM ed 507型胰岛素泵,持续缓慢皮下注射诺和灵R,M SⅡ组采用诺和灵R三餐前、诺和灵N睡前30 m in皮下注射。结果:CSⅡ组与M SⅡ组均能有效控制血糖,但CSⅡ组血糖达标时间和胰岛素用量少于M SⅡ组(P<0.01);CSⅡ组低血糖发生率低于M SⅡ组(P<0.05)。结论:CSⅡ治疗更符合生理状态下胰岛素分泌,较M SⅡ更快更有效地控制高血糖,并减少低血糖发生。

Objective ： To comprehend the value of insulin pump in preoperative diabetic patients. Methods： 106 preoperative diabetic patients were diveded into two groups ：continuous subcutaneous insulin injection（CSⅠ） and multi subcutaneous insulin injection（MSⅡ ）. The Novolin R was injected continuously and slowly by a pump MiniMed 507 U. S. A in CSⅠ group. MSⅡ group,however,was injected the Novolin R 30 minutes before breakfast,lunch and supper,and the NovolinN was given 30 minutes before sleep. Results ：Both CSⅠ and MSⅡ groups were effective on control of serum glucose, but the time and the dose of reaching the expected level of serum glucose were fewer in CSⅠ group than those ig MSⅡ group（P〈0.01）. The incidence rate of hypoglycemia was lower in CS Ⅰ group than that in MSⅡ group（P〈0.05）. Conclusion .. Since CSⅠ couldmimic the physiological insulin secretion, it could control the hyperglycemia much faster and more effectively ,and reduce the hypoglycemia risk.