摘要
感染对患有急性中枢神经系统损伤的患者来说是导致发病率和死亡率主要的原因。最近已经明确中枢神经系统损伤通过脑内特殊的机制显著增加了对感染的易感性：中枢神经系统损伤诱导破坏了免疫系统和中枢神经系统之间原本平衡的相互作用。结果，这种损伤引起了继发的免疫缺陷——中枢神经系统损伤诱导的免疫抑制（CIDS）和感染。CIDS或许可以作为研究大脑对免疫系统控制机制和调节的模型。更重要的是，了解CIDS可使我们制定出有效的治疗策略，这样通过剔除不利于恢复的因素就可以提高由一系列疾病引起的中枢神经系统损伤的预后。
Infections are a leading cause mortality in patients with acute CNS cently become clear that CNS injury of morbidity and injury. It has resignificantly increases susceptibility to infection by brain-specific mechanisms： CNS injury induces a disturbance of the normally well balanced interplay between the immune system and the CNS. As a result, CNS injury leads to secondary immunodeficiency--CNS injury-induced immunodepression（CIDS） - and infection. CIDS might serve as a model for the study of the mechanisms and mediators of brain control over immunity.
