相转移催化合成环丙烷羧酸异丙酯

PHASE TRANSFER CATALYZED SYNTHESIS OF iso-PROPYL CYCLOPROPANECARBOXYLATH

通过固 /液相转移催化 ( PTC)法 ,由 4氯代丁酸异丙酯合成了环丙烷羧酸异丙酯 ,讨论了 PTC种类 ,PTC用量 ,反应温度 ,反应时间 ,原料配比等因素对产率的影响。在最佳反应条件下 ,环丙烷羧酸异丙酯的产率达 92 %。

In this paper, the phase transfer catalyzed synthesis of isopropyl cyclopropanecarboxylate from isopropyl4chlorobutylate was studied, and the effects of types of PTC, amount of PTC, reaction temperature, reaction time and molar ration of reactants on the yield of product were discussed. Under the optimum condition the yield of isopropyl cyclopropanecarboxylate is 92%.