摘要
目的探讨重症急性胰腺炎的早期手术与非手术治疗效果。方法符合重症急性胰腺炎诊断标准的64例患者,其中非手术治疗43例,手术治疗21例。非手术治疗以禁食、胃肠减压、改善胰腺微循环,抑制胰酶分泌,抗感染等为主；手术治疗包括清除坏死胰腺、胰床及腹腔引流、胆囊切除切胆道取石等。将手术治疗21例、非手术治疗43例患者的死亡率和并发症等临床资料进行总结并比较分析。结果 (1)死亡率：比较非手术组死亡2例(4．7％),手术治疗组死亡5例(23．8％)。两组间有显著性差异(P<0．001)。(2)非手术组与手术组并发症发生率的比较：ARDS 16．28％vs 23．8％；肾功能不全9．30％vs 28．57％；休克6．98％vs 14．29％；心功能不全4．65％vs 19．05％；胰腺脓肿2．33％vs 9．52％。两组间有显著性差异(P<0．01)。结论重症急性胰腺炎的早期非手术治疗明显优于早期手术治疗。
Objective To evaluate the therapeutic outcomes of early operative intervention and non operative management of severe acute pancreatitis （SAP）. Methods Mortality and morbidity were analyzed and compared in 64 SAP patients who were divided into two groups ： the operation group （n 21） and non operation group （n= 43）. Results Both mortalityand morbidity of non-operation group was significantly lower than those of operative group （P 〈 0. 01）： mortality： 4. 7% vs 23. 8%; complications..ARDS： 16. 28% vs 23. 8%; renal inadequacy： 9. 30% vs 28. 7%; shock： 6. 98% vs 14.29%; cardiac insufficiency： 4. 65% vs 19. 05%; and pancreatic abscess： 2. 33% vs 9. 52%. Conclusions Non-operative management of SAP at the early stage is advantageous over surgical intervention.
出处
《胰腺病学》
2005年第4期224-226,共3页
Chinese JOurnal of Pancreatology
关键词
胰腺炎
急性
非手术治疗
手术治疗
Severe acute pancreatitis
Non operative management
Surgical intervention
