摘要
目的评价^(18)F-FDG与^(131)I显像在诊断甲状腺癌复发和转移中的价值。方法53例手术病理确诊的甲状腺癌患者,进行甲状腺全切和大剂量^(131)I去除甲状腺治疗,并进行^(18)F-FDG SPECT/CT全身显像和^(131)I全身扫描。结果在39例血清hTg高于正常的患者中,11例患者^(18)F-FDG SPECT/CT全身显像与^(131)I全身扫描均为阳性;2例均为阴性;12例^(18)F-FDG SPECT/CT全身显像阳性,而^(131)I全身扫描阴性;14例^(18)F-FDG SPECT/CT全身显像阴性,而^(131)I全身扫描阳性。在14例血清hTg正常的患者中,^(18)F-FDG SPECT/CT全身显像与^(131)I全身扫描均为阴性。结论^(18)F-FDG SPECT/CT全身显像和^(131)I全身扫描联合显像,在探测甲状腺癌复发和转移病灶中具有重要价值;甲状腺癌细胞对^(18)F-FDG和^(131)I的摄取与肿瘤细胞的分化程度密切相关。
Objective To evaluate the clinical value of ^18F-FDG imaging and ^131I whole body scan in patients of thyroid cancer with metastases. Methods Fifty-three Thyroid cancer patients after total thyroidectomy and ^131I albation of the remaining thyroid were studied by ^18F-FDG imaging and ^131I whole body scan. Results In 39 patients with high levels hTg, there were 11 patients with both ^18F-FDG and ^131I scans positive, 2 patients with both ^18F-FDG and ^131I scans negative, 12 patients with ^18F-FDG imaging positive and ^131I scan negative, 14 patients with ^18F-FDG imaging negative and ^131I scan positive. In 14 patients with normal levels hTg, the findings of ^18F-FDG and ^131I scan were all negative. Conclusion Combination of ^18F-FDG and ^131I whole body imaging has good sensitivity for the detection of recurrent and metastatic thyroid cancer; ^18F-FDG and ^131I uptake of thyroid cancer tissue closely related to the differential grading of thyroid cancer.
出处
《上海第二医科大学学报》
CSCD
北大核心
2005年第12期1267-1269,共3页
Acta Universitatis Medicinalis Secondae Shanghai
