新型止血材料Arista AH在脊柱手术中的临床应用

Clinical application of a novel hemostatic material Arista AH in spine surgery

目的评价一种新型止血材料AristaAH控制脊柱手术中活动性出血的有效性和安全性,并初步探讨其在脊柱手术中的适应证。方法采用随机对照试验,筛选2005年1-5月期间脊柱手术患者52例,随机分为试验组和对照组,试验组术中使用AristaAH止血,对照组采用常规外科手术方法止血,评价两组的止血效果及副作用。结果两组在止血效果及副作用等各项指标评价方面无显著差异(P>0.05)。AristaAH对脊柱后路手术中的出血止血效果等同于常规外科操作技术,优势在于操作简单;对于前路手术中椎体切除过程中的出血止血效果略优于常规操作技术。结论AristaAH是一种安全、有效的脊柱外科术中止血剂,在前后路手术中均有其应用价值。

Objective To evaluate the effectivity and safety of a novel hemostatic material, Arista AH, when it is used to stop active bleeding in spine surgery, and to investigate its indications in spine surgery. Methods A prospective study was designed. Fifty-two patients admitted in our department due to spinal disease between January 2005 to May 2005 were divided randomly into test group and control group. Arista AH was used in test group and routine surgical technique in control group for hemostasis. The bleeding condition after hemostasis in every one minute till stopping bleeding or in five minutes, as well as bleeding volume, operation time, postoperative effusion, etc were used to evaluate the effectivity and side effects. Results No statistical difference was detected between the test group and the control group as far as the related indexes for evaluation of hemosydias and side effects （ P 〉 0. 05 ）. Arista AH has an equal effect of hemostasis in comparison with routine surgical techniques in spine surgery via posterior approach, and its advantage is easy manipulation; In spine surgery via anterior approach, especial in corpectomy, Arista AH seemly manifests better hemostatic effect than routine surgical technique. Conclusion Arista AH is a safe and effective hemostatic material for spine surgery, and it has applied value in surgeries via both anterior and posterior approaches.