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线粒体DNA和端粒与年龄相关性的研究进展 被引量：1

The development of research on correlation of mitochondrial DNA and telomere with individual age
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摘要 用DNA技术从分子水平上推断年龄,已成为法医学和人类学研究领域的新热点。目前用于年龄推断研究的DNA标记主要是线粒体和端粒。本文从线粒体DNA和端粒的概念、线粒体DNA的缺失和突变、端粒长度变化与年龄的相关性等方面对该领域的研究进展进行了综述。旨在为法医实践及进一步的研究提供新的方法和思路。 Estimation of individual age using DNA molecular markers emerges as a new research hotspot in the forensic medicine and anthropology. Mitochondrial DNA （mtDNA）and telomere are the prima- ry DNA markers used in deducing individual age in recent years. In this review, the correlation of mutation and deletion of mtDNA and telomere, and length of telomere with aging is discussed, which may provide a new method or idea for research and practice in forensic medicine.
作者 徐晓玲 郑卫平 黄君键
机构地区 北京人民警察学院 军事医学科学院生物工程研究所
出处 《中国法医学杂志》 CSCD 2005年第6期347-349,共3页 Chinese Journal of Forensic Medicine
关键词 法医物证学 线粒体DNA 端粒 年龄推断 Forensic physical evidence Mitochondrial DNA （ mtDNA ）, Telomere Age estimation
分类号 D919 [医药卫生—法医学] R774.5 [医药卫生—眼科]
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参考文献23

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二级参考文献5

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共引文献6

同被引文献6

  • 1Ou XL, Gao J, Wang H, et o1. Predicting human age with bloodstains by sjTREC quantification[J]. PLoS One ,2012,7(8) : e42412.
  • 2Ren F, Li C, Xi H, eta!. Estimation of human ageaccording to telomere shortening in peripheral blood leukocytes of Tibetan[J]. Am J Forensic Med Pathol, 2009,30(3) :252-255.
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  • 6徐隆昌,易少华,黄代新,杨庆恩.DNA甲基化及其与个体年龄相关性研究[J].中国法医学杂志,2011,26(4):295-297. 被引量：1

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中国法医学杂志
2005年 第6期

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