副神经移位修复C_5上干组织学和图像研究

Study of effect of repair of C_5 and superior trunk using accessory nerve transposition

[目的]通过小间隙副神经移位修复C5、上干后再生神经的组织学和图像分析以了解其移位效果及节省动力神经源的可行性。[方法]40只雄性wistar大鼠,随机分成两组,A组:自体颈静脉桥接行副神经小间隙(2mm)移位于C5神经根,B组:自体颈静脉桥接行副神经小间隙(2mm)吻合于上干,两组的左侧为对照侧。术后12周行组织学和图像分析。[结果]A组有髓神经纤维计数、轴突直径和髓鞘厚度左右侧相比差异无显著性意义(P>0.05),而B组左右侧差异有非常显著性意义(P<0.01)。[结论]副神经移位于C5后神经再生明显优于移位于上干。

[ Objective j To examine the effect of repairing C5 and superior trunk with accessory nerve transposition and the feasibility of saving power nerve source by analysising of histological picture after using small gap autogenous jugular vein bridging anastomosis to perform accessory nerve transposition. [ Method] Forty Wistar male rats were randomly divided into two groups, group A： Accessory nerve was transposed to the 5th cervical nerve root using small gap（ 2 mm） autogenous jugular vein bridging and group B： Accessory nerve was transposed to superior trunk, In both groups, the left side was the control side. Twelve weeks after surgery, analysising of histological picture was carried out. [ Result] The results of axonal diameter, myelinated thickness and the number of myelinated nerve fiber of Group A compared with those of the left side had no significance of difference （ P 〉 0.05 ） while of Group B had a highly significance of difference （P 〈0.01 ）. [ Conclusion] Nerve regeneration after accessory nerve was transposed to the 5th cervical nerve was obviously better than those that accessory nerve was transposed to superior trunk.