瑞芬太尼在无痛胃镜检查中的应用

The application of remifentannil during painless gastroscopy

目的:比较瑞芬太尼复合异丙酚与芬太尼复合异丙酚用于无痛胃镜的效果。方法:选60例要求行无痛胃镜检查的患者随机分成两组,A组(瑞芬太尼组)30例,B组(芬太尼组)30例,两组静注异丙酚1．5-2．0mg/kg后A组静注瑞芬太尼 0．5μg／kg,B组静注芬太尼0．05mg,术中根据患者情况适当追加异丙酚,观察SpO2、HR、SBP的变化,病人的异丙酚用量、检查时间、苏醒时间、可行走时间。结果:苏醒时间和可行走时间A组显著短于B组,具有显著性差异。异丙酚的用量B组稍高于 A组,但无显著性差异。结论:瑞芬太尼较芬太尼复合异丙酚用于无痛胃镜检查具有苏醒快,可行走时间短,镇痛效果满意等优点,而且安全。

Objective To investigate the effects of propofol combined with fentanyl or remifentannil during painless gastroscopy . Methods Sixty patients were randomly divided into two groups, group A （remifentannil , n = 30） and group B （fentanyl , n = 30）. All patients were induced with intravenous propofol （ 1.5 - 2.0 mg/kg ）, then maintained with propofol to provide anesthesia during examination according to the reaction of patient. Intravenous remifentannil （0.5μg/kg） were used in group A, and Intravenous fentanyl （0.05mg） were used in group B. Blood oxygen saturation, heart rate, blood pressure, dosages of propofol ,examination time, revival time and walkable time were recorded and analyzed. Results Revival time and walkable time in group A were significantly shorter than those in group B. Dosages of propofol in group B were little higher than those in group A. Conclusion The application of propofol combined with remifentannil during painless gastroscopy may be safer and more satisfied anesthesia compared with propofol combined with fentanyl.