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Endovascular treatment of cerebral arteriovenous malformations with Onyx embolization 被引量:5

Endovascular treatment of cerebral arteriovenous malformations with Onyx embolization
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摘要 Background In the past 5 years, new treatment materials and techniques offering a different concept in endovascular treatment have been described for cerebral arteriovenous malformations (CAVMs). The aim of this study was to assess the endovascular treatment of CAVMs by using a liquid embolic material, Onyx ( Micro Therapeutics. Inc. , Irvine, CA, USA). Methods From September 2003 to September 2004, Onyx was used to treat 22 patients with CAVMs. Ten AVMS were located in functional areas, 8 in deep cerebral areas, and 4 in the cerebellar hemisphere. The size of CAVMs was about 3 cm in diameter in 5 patients, 3 -6 cm in 11, and more than 6 cm in 6. Results In the 22 patients, Onyx embolization was successful. Nidus occlusion was complete in 3 patients, 〉 90% in 8, 〉 80% and 〈 90% in 6, and 〉 50% and 〈 80% in 5. Complications included transient neurological deficits in 2 patients, and adherence of microcatheter to the site of injection in 2. Conclusions Being non-adhesiveness, Onyx is a safe and satisfactory embolic material in the treatment of CAVMs. But its long-term efficacy awaits further follow-up. Background In the past 5 years, new treatment materials and techniques offering a different concept in endovascular treatment have been described for cerebral arteriovenous malformations (CAVMs). The aim of this study was to assess the endovascular treatment of CAVMs by using a liquid embolic material, Onyx ( Micro Therapeutics. Inc. , Irvine, CA, USA). Methods From September 2003 to September 2004, Onyx was used to treat 22 patients with CAVMs. Ten AVMS were located in functional areas, 8 in deep cerebral areas, and 4 in the cerebellar hemisphere. The size of CAVMs was about 3 cm in diameter in 5 patients, 3 -6 cm in 11, and more than 6 cm in 6. Results In the 22 patients, Onyx embolization was successful. Nidus occlusion was complete in 3 patients, 〉 90% in 8, 〉 80% and 〈 90% in 6, and 〉 50% and 〈 80% in 5. Complications included transient neurological deficits in 2 patients, and adherence of microcatheter to the site of injection in 2. Conclusions Being non-adhesiveness, Onyx is a safe and satisfactory embolic material in the treatment of CAVMs. But its long-term efficacy awaits further follow-up.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2005年第24期2041-2045,共5页 中华医学杂志(英文版)
关键词 cerebral arteriovenous malformations embolization therapeutic Onyx copolymer cerebral arteriovenous malformations embolization, therapeutic Onyx copolymer
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参考文献8

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  • 2潘力.颅内动静脉畸形的伽玛刀治疗[J].中国脑血管病杂志,2005,2(2):49-53. 被引量:3
  • 3梁建峰,伍健伟,何伟文.血管内栓塞治疗脑动静脉畸形[J].中华神经医学杂志,2006,5(4):398-400. 被引量:9
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