期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Genetic determination of osteoporosis in Chinese 被引量：2

Genetic determination of osteoporosis in Chinese
原文传递
导出
摘要 Osteoporosis, one of the major and growing health problems around the world, is defined asa systemic SKeletal olsease cnaracterized by ,uw bone mass and microarchitectural deterioration of bone tissue, with high bone fragility and susceptibility to fractures. In China, 6.97% of the population （ 13 billion ） suffered from osteoporosis in 2000. As far as Hongkong was concerned, Osteoporosis, one of the major and growing health problems around the world, is defined asa systemic SKeletal olsease cnaracterized by ,uw bone mass and microarchitectural deterioration of bone tissue, with high bone fragility and susceptibility to fractures. In China, 6.97% of the population （ 13 billion ） suffered from osteoporosis in 2000. As far as Hongkong was concerned,
作者 XIAO Su-mei LEI Shu-feng DENG Hong-wen
机构地区 Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education Department of Orthopedic Surgery
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2005年第24期2077-2088,共12页 中华医学杂志（英文版）
基金 The study was partially supported by a key project grant fromNational Science Foundation of China (No.30230210)
关键词 CHINESE osteoprosis candidate gene approach Chinese osteoprosis candidate gene approach
分类号 R681 [医药卫生—骨科学]
  • 相关文献

参考文献1

二级参考文献27

  • 1Pocock NA, Eisman JA, Hopper JL, Yeates MG, Sambrook PN, Ebert S. Genetic determinants of bone mass in adults. A twin study. J Clin Invest 1991; 80: 706-10.
  • 2Tylavsky FA, Bortz AD, Hancock RL, Anderson JJB. Families resemblance of radial bone mass between premenopausal mothers and their college-age daughters. Calcif Tissue Int 1989; 45: 265-72.
  • 3Cooper GS, Umbach DM. Are vitamin D receptor polymorphisms associated with bone mineral density? A metaanalysis. J Bone Miner Res 1996; 11: 1841-9.
  • 4Ioannidis JP, Stavrou I, Trikalinos TA, Zois C, Brandi ML,Gennari L, et al. Association of polymorphisms of the estrogen receptor α gene with bone mineral density and fracture risk in women: a meta-analysis. J Bone Miner Res 2002; 17:2048-60.
  • 5Gilsanz V, Loro ML, Roe TF, Sayre J Gilsanz R, Schulz EE.Vertebral size in elderly women with osteoporosis. J Clin Invest 1995; 95: 2332-7.
  • 6Vega E, Ghiringhelli G, Mautalen C, Valzacchi GR. Scaglia H, Zylberstein C. Bone mineral density and bone size in men with primary osteoporosis and vertebral fracture. Calcif Tissue Int 1998; 62: 465-9.
  • 7Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, et al. Prediction of bone density from vitamin D receptor alleles. Nature 1994; 367: 284-7.
  • 8Kobayashi S, Inoue S, Hosoi T, Ouchi Y, Shiraki M, Orimo H. Association of bone mineral density with polymorphism of he estrogen receptor gene. J Bone Miner Res 1996; 3:306-11.
  • 9Han K, Choi J, Moon I, Yoon H, Han I, Min H, et al. Nonassociation of estrogen receptor genotypes with bone mineral density and bone turnover in Korean Pre-, Peri-, and postmenopausal women. Osteooorosis lnt 1999: 9:290-5.
  • 10Willing M, Sowers M, Aron D, Clark MK, Burns T, Bunten C, et al. Bone mineral density and its change in white women:estrogen and vitamin D receptor genotypes and their interaction. J Bone Miner Res 1998; 13: 695-705.

共引文献17

同被引文献58

  • 1章振林.骨质疏松相关基因的研究方向[J].中华医学杂志,2006,86(6):361-362. 被引量：13
  • 2Liu YZ,Wilson SG, Wang L, et al. Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One,2008,3(9) :e3160.
  • 3Andre G, Stuarrt H, Maria L, et al. The association between common vitam in D receptor genevariation sand osteporosis Aparticipant level meta-analysis. Ann Intern Med, 2006,145 : 255- 264.
  • 4Yamada Y, Ando F, N iino N, et al. Assiciation of a poly- morphism of the collagen lalphal geng with bone mineral density in posm enopausal Japanese wamen. Hum Biol,2005,77 ( 1 ) :27- 36.
  • 5Ue|and T,Bollerslev J, Wilson SG, et al. No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women. Bone, 2007,40 ( 1 ) : 175-181.
  • 6Liu YZ,Pei YF, Lin JF, et al. Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. PLoS One,2009, 4 (8) : e6827.
  • 7Kobayashi S, Inoue S, Hosoi T, et al. Association of bone mineral density with polymorphism of the estrogen receptor gene [J].J Bone Miner Res,1996,11(3) :306 -311.
  • 8Ioannidis JP, Stavrou I, Trikalinos TA, et al. ER-alpha Genetics Meta-Analysis Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women : a meta-analysis [ J ]. J Bone Miner Res, 2002,17( 11 ) :2048 -2060.
  • 9Ioannidis JP, Ralston SH, Bennett ST, et al. Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes [J]. JAMA,2004,292(17) :2105 -2114.
  • 10Nam HS, Shin MH, Kweon SS,et al. Association of estrogen receptor-alpha gene polymorphisms with bone mineral density in postmenopausal Korean women [ J ]. J Bone Miner Meta, 2005,23 ( 1 ) : 84 - 89.

引证文献2

二级引证文献7

Chinese Medical Journal
2005年 第24期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部