瞬态诱发耳声发射甘油试验对初次发作眩晕的诊断价值

The diagnostic value of TEOAE-glycerine test in patients with vertigo on the first attack

目的:探讨瞬态诱发耳声发射(TEOAE)甘油试验对初次发作眩晕的诊断价值。方法:对28例眩晕初次发作,纯音听阈(PTT)正常,无耳鸣及耳胀满感,病史及临床特征不支持非梅尼埃病的眩晕患者进行PTT及TEOAE甘油试验。结果:28例中,4例服甘油后PTT及TEOAE均无改变,其各项观察值在正常范围;TEOAE甘油试验阳性20例(单耳16例,双耳4例),其中2例(2耳)服甘油前TEOAE未引出,服甘油后可引出,TEOAE甘油试验阳性耳,服甘油前、后TEOAE各观察值均低于正常人标准;4例PTT甘油试验阳性,但服甘油前后TEOAE均未引出。结论:TEOAE甘油试验可作为将首次发作眩晕而听力正常患者早期诊断为梅尼埃病及鉴别诊断的常规方法。

Objective： To investigate the diagnostic value of transiently evoked otoacoustic emissions （TEOAE） combined with glycerine test in patients with vertigo on the first attack. Method：PTT and TEOAE-glycerine test were conducted on the 28 patients who suffered the first attack of vertigo without hearing loss, tinnitus or a sensation of fullness in the ear. At the same time, history and clinical manifestation of the patients were not supportive for the non-Meniere＇s disease. Result：Among the 28 cases, four of them had nothing changed on the PTT and TEOAE parameters after glycerol administration, all of the indexes were in the normal range. Among the 20 positive cases in the TEOAE-glycerine test （unilateral ear 16 cases, bilateral ears 4 cases）, TEOAE for 2 cases were not evoked before glycerol administration, while it was evocable after glycerol administration. For the positive ears, all of the parameters of TEOAE were lower than those in the normal standard before and after glycerol adminstration; there were 4 positive cases in the PTT glycerine test, however, both TEOAE were not evoked before and after glycerol administration. Conclusion, TEOAE-glycerine test can be used as a routine method for the early diagnosis of Meniere＇s disease and differentiating diagnosis in the patients who suffer vertigo on the first attack with normal hearing.