麻城市321例红斑性肢痛症临床分析

Clinical Analysis of 312 Cases of Erythromelalgia in Macheng City

本文报告红斑性肢痛症321例临床分析,其中发病期发热55例,2例有异型淋巴细胞及中毒颗粒,46例进行补体结合试验,阳性率65.2％,60例血清免疫球蛋白检测,13例发热期IgM明显增高,发病后期IgG、IgA、CIC明显增高,结合流行病学调查,提示发病机理可能为Ⅲ型变态反应,推测可能是某种病毒致病。

Clinical analysis of 312 cases of erythromelalgia were reported, 55of which have a fever in the onset period of the disease. There were toxic granules within the leukocyte and poikilolymphocyte in 2 cases. Complement fixation test were performed in 46 patients, the positive rate was 65.2%. Serum immunglobulin was measured in 60 cases. The IgM of 13 patients was obviously elevated in the phase of fever. the IgG, IgA and CIC were much more significantly elevated in the later stage of the illness. The above statement and an epidemicological survey suggest that the mechanism of the disease may be type Ⅰ hypersensitivity, and we guess that it was caused by some virus.