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罗哌卡因与布比卡因术后病人硬膜外自控镇痛的疗效观察

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摘要 目的:观察罗哌卡因与布比卡因术后病人硬膜外自控镇痛(PCEA)的各自疗效并进行评估。方法:60例择期经膀胱前列腺摘除病人。随机分R、B两组各30例。术中均采取L2-3硬膜外阻滞麻醉,给0.75%罗哌卡因和2%利多卡因对半混合液,术后保留硬膜外导管。术毕两组均给负荷量罗利对半混合液5ml。背景输入2ml/h,PCA量0.5ml,锁定时间15min。PCA药液R组0.15%罗哌卡因+芬太尼3ug/ml+地塞米松0.1mg/ml+Ns共100ml,B组0.15%布比卡因+芬太尼3ug/ml+地塞米松0.1mg/ml+NS共100ml。术后6、12、24、48h分别观察BP、HR、RR、SpO2、疼痛评分(VAS)、恶心、呕吐及下肢麻木。结果:两组病人镇痛效果无统计学差异(P〉0.05),恶心、呕吐的发生率也无差异(P〉0.05),下肢麻木的发生两组间差异有显著性(P〈0.05)。结论:罗哌卡因用于PCEA不但与布比卡因有相同的疗效,而且优于布比卡因。
出处 《医用放射技术杂志》 2006年第1期79-81,共3页 Journal of Medical Radiology Technology
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参考文献7

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二级参考文献4

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