期刊文献+

老年妇女子宫内膜癌预后高危因素分析 被引量:2

下载PDF
导出
摘要 目的探讨影响老年子宫内膜癌预后的高危因素.方法回顾分析33例老年妇女内膜癌的临床资料和生存情况,评价影响其预后的因素.结果单因素分析显示,内膜癌的易患因素不影响老年内膜癌预后(P>0.05).Ⅰ~Ⅲ期的2年生存率为90%,78%和50%,差异有显著性(P<0.05).G1~G3的2年生存率为88%,78%和75%,差异无显著性(P>0.05).≥1/2肌层浸润的2年生存率为39%,显著低于<1/2肌层浸润的100%(P<0.001).有无宫颈转移的3年生存率、有无附件转移的2年生存率、腹腔冲洗液有无癌细胞的1年生存率分别为27%和83%,50%和80%,25%和96%,差异均有显著性(P<0.05).多因素分析上述因素均与预后无关.结论 FIGO分期、深肌层浸润、宫颈转移、附件转移及腹腔冲洗液有癌细胞是影响老年妇女内膜癌预后的高危因素,老年人的预后不良可能和高危因素的综合影响有关.
出处 《广东医学》 CAS CSCD 北大核心 2005年第12期1694-1695,共2页 Guangdong Medical Journal
  • 相关文献

参考文献6

  • 1Buttin BM, Powell MA, Mutch DG, et al. Increased risk for hereditary nonpolyposis colorectal cancer- associated synchronous and metachronous malignancies in patients with microsatellite instability positive endometrial carcinoma lacking MLH1 promote methylation. Clin Cancer Res, 2004, 10(2):481.
  • 2Toda T, Oku H, Khaskhely NM, et al. Analysis of microsatellite instability and loss of heterozygosity in uterine endometrial adenocarcinoma. Cancer Genet Cytogenet,2001,126(2):120.
  • 3王志启,王建六,魏丽惠.子宫内膜癌合并症146例临床分析[J].中华妇产科杂志,2003,38(6):350-353. 被引量:19
  • 4彭芝兰.女性生殖器肿瘤[A].丰有吉主编.妇产科学[M].北京:人民卫生出版社,2002.286-292.
  • 5Citron JR, Sutton H, Yamada SD, et al. Pathologic stage Ⅰ~Ⅱ endometrial carcinoma in the elderly: radiotherapy indications and outcome. Int J Radiat Oncol Biol Phys,2004,59(5): 1432.
  • 6Fadare O, Mariappan MR, Hileeto D, et al. Upstaging based solely on positive peritoneal washing does not affact outcome in endometrial cancer. Med Pathol, 2005,18(6) ,673.

二级参考文献2

  • 1郭燕燕,孙可淳,麦永嫣,石雪君.子宫内膜癌153例临床分析[J].北京医科大学学报,1994,26(4):261-263. 被引量:3
  • 2彭芝兰.子宫内膜癌发病率[A].曹泽毅 主编.中华妇产科学[C].北京:人民卫生出版社,1999.1845-1846.

共引文献18

同被引文献17

  • 1胡喜珍,舒慧芳,陈燕辉,陈茜.339例老年妇科手术临床分析[J].国际医药卫生导报,2006,12(21):37-39. 被引量:3
  • 2赵晓东,张毅.子宫内膜癌的治疗[J].中国肿瘤临床,2007,34(1):56-59. 被引量:6
  • 3Fakiris AJ,Randall ME.Endometrial carcinoma:the current role of adjuvant radiation.J Obstet Gynaecol,2009,29(2):81-89.
  • 4Arabi H,Guan H,Kumar S,et al.Impact of microsatellite instability (MSI) on survival in high grade endometrial carcinoma.Gynecol Oncol,2009,113(2):153-158.
  • 5Steiner E,Eicher O,Sagemuller J,et al.Multivariate independent prognostic factors in endometrial carcinoma:a clinicopathologic study in 181 patients:10 years experience at the Department of Obstetrics and Gynecology of the Mainz University.Int J Gynecol Cancer,2003,13 (2):197-203.
  • 6Lachance JA,Everett EN,Greer B,et al.The effect of age on clinical/pathologic features,surgical morbidity,and outcome in patients with endometrial cancer.Gynecol Oncol,2006,101 (3):470-475.
  • 7Jolly S,Vargas CE,Kumar T,et al.The impact of age on long-term outcome in patients with endometrial cancer treated with postoperative radiation.Gynecol Oncol,2006,103(1):87-93.
  • 8Zusterzeel PL,Bekkers RL,Hendriks JC,et al.Prognostic factors for recurrence in patients with FIGO stage Ⅰ and Ⅱ,intermediate or high risk endometrial cancer.Acta Obstet Gynecol Scand,2008,87(2):240-246.
  • 9Jobsen JJ,Lybeert ML,van der Steen-Banasik EM,et al.Multicenter cohort study on treatment results and risk factors in stage Ⅱ endometrial carcinoma.Int J Gynecol Cancer,2008,18 (5):1071-1078.
  • 10Fujimoto T,Nanjyo H,Fukuda J,et al.Endometrioid uterine cancer:histopathological risk factors of local and distant recurrence.Gynecol Oncol,2009,112(2):342-347.

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部