踝臂指数与冠状动脉病变严重程度的相关性分析

Clinical study on correlations of abnormal ankle-brachial index with the extent of coronary atherosclerosis lesions

目的明确踝臂指数(ABI)与冠状动脉病变严重程度的关系。方法入选的116例行冠状动脉造影或介入治疗的患者,对其进行ABI测量、血液生化检查、病史采集及冠状动脉造影;分析ABI与冠状动脉病变严重程度的相关性。结果冠状动脉病变严重组与非严重组之间ABI异常率比较差异有统计学意义(16.4%vs 59.2%,P<0.05);回归分析提示ABI≤0.90是惟一可以预测冠状动脉严重病变的因子。结论ABI≤0.90可以预测冠状动脉严重病变。

Objective To examine the correlation between ankle-brachial（ABI） and the extent of coronary atherosclerosis lesions in Chinese. Methods Patients who had taken the coronary angiography or percutaneous coronary intervention were recruited from the cardiac catheterization laboratory. All the patients underwent ABI measurement, hemostatic factors evaluation, history collection and elective coronary angiography. The correlation between ABI and the extent of coronary atherosclerosis lesions was analysed. Results There were significant differences between severe coronary artery disease（CAD） （3-vessel disease plus left main disease） and non-severe CAD （no CAD plus 1- and 2-vessel disease） in the ratio of abnormal ABI （16.4% vs 59.2 %, P d0.05）. The severity of CAD was positively correlated with ABI≤0.90. Conclusion ABI≤0.90 can predict the presence of 3-vessel or left main CAD.