口腔低分化恶性肿瘤的免疫组织化学分析

An Immunohistochemical Observations on Poor Differentiated Malignant Tumors of Maxillofacial Areas

用免疫组织化学方法对１６例未完全确诊的低分化恶性肿瘤进行分析。结果表明，原疑为恶性淋巴瘤的３例，疑为间叶性恶性肿瘤的２例及癌的６例，均为Ｄｅｓｍｉｎ，Ｖｉｍｅｎｔｉｎ及Ｍｙｏｓｉｎ阳性表达，被确诊为横纹肌肉瘤，另５例原疑为癌的病例显示ＬＣＡ及Ｖｉｍｅｎｔｉｎ阳性表达，被确诊为恶性淋巴瘤。结果提示，选用适当的标记物进行免疫组织化学标记，有助于提高低分化恶性肿瘤的诊断准确性。

Specimens of 16 cases poor differentiated malignant tumors of maxillofacial areas were selected for this immunohistochemical study. The results showed that 16 cases,11 cases were confirmed to be rhabdomyosarcoma(RMS) as their positive expression of Myosin, Desmin and Vimentin, the other 5 cases were rectified as non-Hodgkin's lymphoma(NHL)because of their positive expression of LCA and Vimentin. The results suggest that the expression of specific antigen by immunohistochemical methods can increase the accuracy in diagnosis of the poor differentiated malignant tumors of maxillofacial areas such as RMS and NHL.