摘要
鸦胆子油乳颗粒剂1．4，2．8g（鸦胆子油）／kg／d，连续灌胃3天，显著抑制幽门结扎大鼠胃溃疡的形成；1．2g（鸦胆子油）／kg／d，连续灌胃3天，显著抑制阿斯匹林（ASP）所致小鼠胃溃疡的形成；0．6，1．8g（鸦胆子油）／kg／d，连续灌胃3天，对小鼠束水应激性胃溃疡有显著抑制作用；0．5，1．0g（鸦胆子油）／kg／d，连续灌胃9天，显著抑制大鼠醋酸慢性胃溃疡的形成；0．5，1．0g（鸦胆子油）kg／d，连续灌胃3个月，对氨水所致大鼠慢性萎缩性胃炎（CAG）有显著抑制作用．
Emulsive granules of Seed oil of Brucea Jaranica significantly inhibits pyrolus ligation induced gastric ulcer in rats (1.4, 2.8 g/kgｘ3d. ig), aspirin induced gastric ulcer in mice (1. 2 g/kgｘ 3d, ig ), water-immersion stress induced gastric ulcer in mice (0.6, 0. 8g/kgｘ 3d,ig),and acetic acid induced chronic gastric ulcer in rats (0. 5, 1. 0 g/kgｘ 9 d,ig). The emulsive granules of seed oil of Brucea Jaranica (0. 5, 1. 0 g/kgｘ90d, ig) was also found to possess the effects against inflammatory infiltration and atrophy of gastric glands in chronic gastritis induced by agua ammoniae.
出处
《沈阳药科大学学报》
CAS
CSCD
1996年第1期13-17,共5页
Journal of Shenyang Pharmaceutical University
关键词
鸦胆子
油乳颗粒剂
雷尼替丁
胃溃疡
胃炎
Emulsive granules of seed oil of Brucea Jaranica
Ranitidine hydrochloride
Gastric ulcer
Chronic gastritis
