恶性肿瘤患者深部真菌感染临床分析

Clinical analysis of fungus infection in patients with malignant tumor

目的 了解恶性肿瘤患者医院深部真菌感染的临床特点。方法 对我院2003—2004年62例发生医院真菌感染的恶性肿瘤患者病历资料进行回顾性分析。结果 恶性肿瘤患者真菌感染死亡率为22．4％。其原发病以急性白血病、消化道肿瘤和肺癌居前三位。真菌感染发生部位以下呼吸道最多（68％）。真菌分类以白色念珠茵为主（66％）。结论恶性肿瘤患者自身免疫力低下是发生医院真菌感染的主要原因，控制的关键在于预防。

Objective To study the clinical features of hospital fungus infection in patients with malignant tumor. Methods The data of a total of 62 cases of malignant tumor who inflicted hospital fungus infection were retrospectively analysed. Results The death rate of fungus infection in these malignant tumor patients was 22.4%. Acute leukemia, digestive tract tumors, and lung cancer were the most commonly seen tumors for these patients. The majority of the infection sites was located in lower respiratory tract（ 68%）. The most common pathogen was candida albicans （66%）. Conclusion Low immunity is the main reason for hospital fungus infection in these patients. The key to control hospital fungus infection is prevention.