不同病理类型肺癌核素骨显像结果分析

Clinical analyses of radionuclide bone imaging with lung cancer of different pathological types

目的:探讨不同病理类型肺癌骨转移的特点和规律。方法:回顾性分析138例经病理学证实的不同病理类型肺癌患者核素骨显像结果。结果:①肺癌骨转移发生率为62.3%,其中腺癌73.8%,鳞癌55.8%,混合癌50%,未分化癌47.1%。腺癌较其它病理类型肺癌更易发生骨转移(P<0.05);②肺癌骨转移部位以胸部骨骼为最多,其次为脊柱和骨盆;腺癌以胸部及骨盆为主,鳞癌以胸部和脊柱为主。结论:肺癌患者核素骨显像对肺癌的分期、不同病理类型治疗方案选择及预后评估有重要的临床参考价值。

Objective ：To investigate the characteristics and regularity of skeletal metastases with lung cancer of different pathological types. Methods. Radionuclide bone imaging was analysed retrospectively in 138 cases of lung cancer of different pathological types proven by pathology. Results ,①Total skeletal metastatic rate of lung cancer was 62. 3%. The lung tumors of the patients with bone metastasis can be divided as follows; 73.8%in adenocarcinoma , 55.8% in squammous carcinoma, 50.0% in adeno-squamo- carcinoma, 47. 1% in undiferentiated carcinoma . There were significant differences among adenocarcinoma with other different pathological types （P〈0. 05 ）;② Thoracic bones were the frequently involved metastatic sites , spine and pelvis were the next . adenocarcinoma metases frequently involved thoracic and pelvis, squammous carcinomametasized frequently involved thoracic and spine. Conclusion ,Rradionuclide bone imaging is useful for staging,treating and prognosing lung cancer.