卵巢卵黄囊瘤27例临床与病理分析

Clinical and pathological analysis in 27 cases of yolk sac tumour of the ovary

目的：探讨卵巢卵黄囊瘤临床与病理特点。方法：分析研究27例卵巢卵黄囊瘤临床资料、病理检查并随访其发病规律与特点。结果：临床Ⅰ期13例及临床Ⅱ期2例（以上均为单纯型）随访2～21年均健在；临床Ⅰ期（混合型）1例术后3年死亡，临床Ⅱ期3例（内有混合型1例）术后1年内死亡，1例术后3年死亡。临床Ⅲ期术后1年死亡及术后2年死亡各2例，临床Ⅳ期1例术后1个月死亡；失访2例。结论：卵巢卵黄囊瘤属恶性肿瘤，预后与临床分期及组织学类型密切相关，手术治疗并配合VAC或PVB化疗可以明显改善预后。

Objective： To reveal the clinical and pathological characteristics of yolk sac tumour of the ovary. Methods： The clinical and pathological data and characteristics of 27 cases of yolk sac tumor of the ovary were studied. Results： Thirteen cases of stage Ⅰ（simple type） and 2 cases of stage Ⅱ （simple type） were alive 2 to 21 years after operation. One case of stage I （complex type） died 3 years after operation. Three cases of stage Ⅱ died within 1 year after operation, in which 1 case was complex type and 1 case died 3 years after operation. Two case of 4 cases of stage Ⅲ died 1 year after operation, 2 cases died 2 years after operation. One case of stage IV died 1 month after operation,2 cases lost in following up. Conclusion ： Pathologic types of yolk sac tumour of the ovary have close relationship with following up and clinic stage. The prognosis can be improved if the patients are treated by operation with VAC or PVB chemical therapy.