微泵静脉注射麻黄素预防剖宫产术硬膜外麻醉的循环抑制

Ephedrine infusion intravenously used in prevention of blood cycle inhibition induced by epidural-anesthesia in women underwent cesarean section

目的：评价微泵静脉注射麻黄素预防剖宫产术硬膜外麻醉循环抑制的效果。方法：78例ASAⅠ-Ⅱ级足月产妇在硬膜外麻醉下行剖宫产术，随机分A、B两组（n=39），两组产妇麻醉前均预先静脉输入平衡液500ml，麻醉后实验组（A组）以1mg min^-1速度微泵静脉注射麻黄素，然后根据血压变化调整麻黄素注射速度；对照组（B组）继续输入平衡液。结果：A、B两组产妇的一般情况无显著性差异，术中的麻醉效果满意（P〉0．05）。B组麻醉后循环抑制较明显，主要表现为血压下降，心率减慢；A组则循环稳定。结论：微泵静脉注射麻黄素预防剖宫产术硬膜外麻醉的循环抑制安全有效。

Objective： To evaluate the preventive effects of ephedrine infusion intravenously on the low blood pressure after induction of epidural anesthesia in women underwent cesarean section. Methods： 78 ASA Ⅰ-Ⅱ cesarean section women were divided randomly into A and B two groups （ n = 28 ） . All women received Ringer＇s solution 500 ml before induction of anesthesia. Women in group A received ephedrine infusion intravenously at a rate of 1 mg/min, thereafter the infusing rate of ephedrine was regulated according to the changes of blood pressure. Women in group B had Ringers solution continually. Results： There were no significant differences in the general characters between the two groups （P〉0.05） . All have satisfactory anesthesia. After induction of anesthesia, women in group B had a significant reduction in BP （P〈0.05）, whereas group A had a stable BP. Conclusion： Ephedrine infusion intravenously can prevent the low blood pressure effectively and safely after induction of epidural anesthesia in women with cesarean section.