摘要
目的探讨老年高血压病患者静息心率(resting heart rate,RHR)与尿白蛋白排泄率及微量白蛋白尿阳性率的关系。方法选择老年高血压患者155例,平均年龄(67.9±7.3)岁,分布于60~85岁。尿白蛋白排泄率在30~300mg/24h定为尿微量白蛋白尿阳性。按收缩压(SBP)水平分为3组:SBP〈160mmHg(1mmHg≈0.133Kpa),160mmHg≤SBP〈180mmHg,SBP≥180mmHg。在以上每一组中,又按RHR水平分为:RHR1组,RHR〈70次/min(48例);RHR2组,70次/min≤RHR〈80次/min(62例);RHR3组,RHR≥80次/min(45例),比较其尿白蛋白排泄率及微量白蛋白尿阳性率。结果各组中随RHR增加,尿白蛋白排泄率依次增高(P〈0.01);微量白蛋白尿阳性率依次增高(P〈0.01)。结论随着RHR的升高,尿白蛋白排泄率及微量白蛋白尿阳性率均相应升高。RHR的增加是老年高血压患者早期肾损害的预测因素。
Objective To investigate the relationship between resting heart rate (RHR) and urinary albumin excretion (UAE) and microalbuminuria (Malb) in senile essential hypertension. Methods All 155 elderly essential hypertensive patients (nge:60- 85 years) were divided into three groups according to the levels of systolic blood pressure (SBP): SBP 〈 160mmHg( 1 mmHg≈ 0.133kPa), 160mmHg ≤ SBP 〈 180mmHg, SBP≥ 180mmHg. Each of the groups mentioned above were divided into 3 groups according to the levels of RHR [ RHR1 group : RHR1 〈 70 beats/minute ( bpm ) ; RHR2 : 70bpm ≤ RHR 〈 80bpm ; RHR3 ≥ 80bpm ]. Microalbuminuria was defined as UAE of 30 - 300mg/24h. The UAE and Malb in three groups were compared respectively. Results The increasing of UAE and Microalbuminuria were accordingly with increasing of RHR. Conclusion UAE and prevalence of Malb were keeping with ascending level of RHR. RHR was a predictor of early renal damage in elderly essential hypertensive patients.
出处
《四川医学》
CAS
2006年第1期38-40,共3页
Sichuan Medical Journal