针刺曲池和太冲对高血压病不同证型的疗效

Research of Needling Quchi and Taichong Points on Treating Hypertension Patients with Different Syndrome

目的:观察针刺曲池、太冲穴治疗不同证型高血压病患者的临床疗效及对患者血中血管紧张素转换酶(ACE)和内皮素(ET)含量的影响;并探讨曲池、太冲穴针刺降压的作用机制。方法:将高血压病患者80例随机分为肝火亢盛、痰湿壅盛、阴虚阳亢与阴阳两虚四组,均运用针刺治疗。用放免法测定血浆ET含量和化学比色法测定血清ACE含量。结果:1个疗程后,痰湿壅盛组和肝火亢盛组降压疗效明显优于阴虚阳亢组和阴阳两虚组(P<0.01),阴虚阳亢组和阴阳两虚组比较差异也有显著性意义(P<0.01)。1个疗程后血浆中ET均有不同程度下降,下降的程度依次为痰湿壅盛组>肝火亢盛组>阴虚阳亢组>阴阳两虚组;阴虚阳亢组、肝火亢盛组、痰湿壅盛组三组与治疗前比较,差异均有显著性意义(P<0.01,P<0.05)。血清ACE均有不同程度升高,依次为肝火亢盛组>痰湿壅盛组>阴虚阳亢组>阴阳两虚组。阴虚阳亢、肝火亢盛、痰湿壅盛三组与治疗前比较,差异均有显著性意义(P<0.01)。结论:高血压证型与病情的严重程度有关,针刺曲池、太冲可调节高血压病患者血中ACE、ET的含量。

Objective：To observe the effect of needling Quehi and Taiehong Points on treating hypertension patients with different syndrome and the influence on blood levels of angiotension converting enzyme （ACE） and endothelin （ET）, as well as to explore the mechanism of acupuncture. Methods： 80 hypertension patients were randomly divided into flaring liver- fire group （A）, interior retention of phlegm dampens group （B）, deficiency of Yin with excess of Yang group （C） and deficiency of both the Yin and Yang group （D） treated by acupuncture. Changes of plasma ET were determined by radio immunoassay （RIA） and serum ACE content by chemical colorimetry. Results： After one course of treatment, the effect in Group A and Group B was obviously better than that in Group C and Group D （ P 〈 0.01 ）, while Group C and Group D had also significant difference （P 〈 0.01 ）. Contents of plasma ET in all groups were significantly decreased. The decrease degree was Group B, A, C and D in order. Contents of serum ACE in Group C, A and B had significant difference compared with those before treatment （P 〈 0.01, P 〈 0.05 ）. Contents of serum ACE in all groups were significantly increased. The increase degree was Group A, B, C and D in order. Contents of serum ACE in Group C, A and D had significant difference compared with those before treatment （P 〈 0.01 ）. Conclusion： Needling Quchi and Taichong points has curative effect on treating hypertension patients with all sorts of syndrome. The effects in Group A and B are better. It also shows different syndrome of hypertension has been related to serious extent of disease. Since needing Quchi and Taichong points can regulate the blood levels of ACE and ET.