期刊文献+

ACEI合AngⅡ受体拮抗剂治疗心衰合并心房颤动 被引量:4

下载PDF
导出
摘要 目的:探讨血管紧张素转换酶抑制剂(培哚普利)联合血管紧张素Ⅱ受体拮抗剂(氯沙坦)对慢性心力衰竭(CHF)合并心房颤动的疗效。方法:慢性心衰合并阵发性房颤患者65例随机分为常规治疗(对照组)30例和治疗组35例,治疗组除常规治疗并加用培哚普利(2~8mg/天)基础上,再给予氯沙坦(25~100mg/天)口服,治疗前及治疗后4~6周分别行常规超声心动图检查,临床评价心功能。结果:治疗组治疗后房颤复发率17.1%,明显低于对照组46.6%,差异有显著性意义,P<0.05;治疗组心功能分级及心排血量(CO)、左室射血分数(LVEF)等较对照组明显改善。结论:血管紧张素Ⅱ受体拮抗剂联合血管紧张素转换酶抑制剂能明显改善慢性心力衰竭合并心房颤动患者的心功能,减少房颤的复发率。
出处 《浙江中西医结合杂志》 2006年第1期19-20,共2页 Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献6

二级参考文献28

  • 1[1]Brunner HP,Rocca MD,Vaddadi G,et al. Recent insight into therapy of congestive heart failure: focus on ACE inhibition and angiotensin-Ⅱ antagono ism[J].J Am CollCardiol,1999,33(5):1163-1173.
  • 2[2]Cleland JG,Morgan K. Inhibition of the renin-angiotension-aldosterone system in heart failure:new insights from basic clinical research[J]. Curr Opin Cardiol, 1996,11: 252-262.
  • 3[3]Struthers AD. Angiotensin Ⅱ receptor antagonists for heart failure[J].Heart,1998,80:5-6.
  • 4[4]Liu YH,Yang XP,Sharov VG,et al. Effects of angiotension-converting enzyme inhibitors and angiotensin Ⅱ type Ⅰ receptor antagonists in rats with heart failure. Role of kins and angiotensin Ⅱ type Ⅱ receptors[J]. J Clin In vest, 1997,99(8): 1926-1935.
  • 5[5]Ruzicka M, Baoxue Y,Frans HH,et al. Effects of enalapril versus Iosartan on regression of volume overload induced cardiac hypertrophy in rats[J]. Circu lation , 1994,90( 1 ): 484-491.
  • 6[6]Schieffer B,Wirger A,Meybrunn M,et al. Comparative effects of chronic an giotension-converting enzyme inhibitors and angiotensin Ⅱ type I receptoe blockade on cardiac remodeling after myocardial infarction in the rat[ J ]. Cir culation, 1994,89(5): 2273-2282.
  • 7[7]Kim S,Zhan Y,Izumi Y,et al. Cardiovascular effects of combination of perindopril,candesartan,and amlodipine in hypertensive rats[J ]. Hyperten sion, 2000,35 (3): 769-774.
  • 8[8]Turcani M,Rupp H. Development of pressure overload induced cardiae hy pertrophy is unaffected by long-term treatment with Iosartan[ J ]. Moll Cell Biochem, 1998, 188:225-233.
  • 9[9]Shen YT,Wiedmann RT,Greenland BD,et al. Combined effects of angioten sion converting enzyme inhibitors and angiotensin Ⅱ receptor antagonism in conscious pigs with congestive heart failure [J ]. Cardiovasc Res, 1998, 39(2):413-422.
  • 10[10]Richer C,Fornes P,Cazaubon C,et al. Effects of long-term angiotensin ⅡAT1 receptor blokade on survival,hemodynamic and cardiac remodeling in chronic heart failure in rats[J ]. Cardiovasc Res, 1999,41 ( 1 ): 100-108.

共引文献2455

同被引文献97

引证文献4

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部