1-烷基-1'-乙酰基二茂铁的合成

Synthesis of 1-Alkyl-1'-acetylferrocenes

用新方法合成了1-烷基-1'-乙酰基二茂铁,该法与传统方法相比易于得到单一产物.通过7种1-烷基二茂铁甲酸与三氯化磷作用形成酰氯,再与乙酰乙酸乙酯的钠盐进行反应,皂化脱羧得到1-烷基-1'-乙酰基二茂铁化合物,用元素分析、红外光谱、核磁共振氢谱确定了化合物的结构.

A novel synthetic method for 1-alkyl-l＇-acetylferrocenes （CnH2n＋1-Fc-COCH3, n=2-8, Fc= C5H4FeC5H4） was developed. Alkylferrocenoyl chlorides were added into the solution of sodium methoxylate with ethyl acetoacetate, then hydrolytic decarboxylation led to 1-alkyl-1＇-acetylferrocenes. The compositions and structures of all compounds were characterized by elemental analysis, IR and 1H NMR spectra.