早产儿凝血功能的监测及临床意义

Detection and clinical significance of coagulation function in premature infants

目的探讨早产儿凝血功能的改变。方法对37例早产儿和15例足月儿进行PT、APTT、TT、Fbg检测。结果无论孕周大小的早产儿PT、APTT、TT均延长,<35周者PT、APTT、TT与≥35周早产儿相比差异有显著性(P<0.05),Fbg相比无统计学差异(P>0.05)。结论早产儿处于低凝血因子状态,易患出血性疾病,应及早监测凝血指标,采取有效预防措施,纠正出凝血障碍。

Objective To study the change of the coagulation function in premature infant. Methods We measured the changes of the prothrombin time （ PT）, activated partial thromboplastin time （ APTT）, thrombin time （TT） and fibrinogen （Fbg） in thirty - seven premature infants and fifteen mature infants. Results The PT. APTY and TT all became longer obviously in premature infants and they lengthened more obviously in the premature infants who were below thirty - five weeks than those above thirty - five weeks. But Fbg was no difference in all infants Conclusion The premature infants were lacking in clotting factor so they tend to have bleeding disease.