疣状胃炎1897例临床分析

Clinical analysis of 1 897 cases of verrucose gastritis

目的探讨疣状胃炎的临床表现、内镜及病理特点。方法对1897例患者的临床、病理及Hp等进行回顾性分析。结果疣状胃炎的临床症状缺乏特异性。胃镜下特点为:胃黏膜上形成带脐窝的隆起性病变,主要发生部位在胃窦部1681例(88.6%),其次是胃体胃窦部118例(6.2%)。年龄以30～59岁居多,男性多于女性。病理检查都有不同程度的炎症,有的伴有肠上皮化生及不典型增生。HP阳性感染率为61.2%。结论胃镜检查是诊断该病的最佳手段。Hp感染与该病的发生有关。因此,Hp阳性者应予抗Hp治疗。

[Objective] To investigate the clinical symptom, endoscopy manifestations, and pathological features of verrucose gastritis..[Method] Documents of 1 897 patients with verrucose gastritis were reviewed and analyzed. The clinical symptom, pathological changes, and HP infection were characterized. [Result] No clinical symptom was specific for verrucose gastritis. All patients underwent endoscopy, it revealed that mucosal granula with foveola is special manifestation for verrucose gastritis. This change was mainly found in gastric antrum （88.6%）, more than that in gastric body （6.2%）. Most of patients were 30-59 years old, male seems more liable to verrucose gastritis than female. Inflammations on different degrees were found in all patients with pathological examination, intestinal metaplasia （/M） and atypical hyperplasia were also found in some cases. In this group, the positive rate of HP was 61.2%. [Conclusion] To diagnose the verrueose gastritis, gastroscopy examination is the best method. There are some relationship between HP infection and verrueose gastritis. Consequently, patient with HP infection should be treated with anti-HP drug.