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苯并咪唑铕(Ⅲ)配合物的合成及其与DNA的相互作用 被引量:2

Synethesize of Europium(Ⅲ) Complex and the Interaction Between the Complex and DNA
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摘要 合成并表征了2′6-二(苯并咪唑-2′)吡啶(H2bzimpy)和铕(Ⅲ)的配合物,用电子吸收光谱、荧光光谱和粘度测定研究了配合物与DNA的相互作用,推测了配合物与DNA的结合模式. Europium(Ⅲ) complex having planar tridentate ligand, H2 bzimpy, where H2 bzimpy is 2,6-bis (benzimidazol-2-yl) pyridine was synthesized and characterized by UV, infrared spectroscopy and fluorescence spectra. The binding of this complex with calf thymus DNA has been investigated by absorption, luminescence titration and viseositv measurements. The results suggest that Europium (Ⅲ ) complex partly intercalates into DNA base pairs via the ligand H2 bzimpy.
出处 《湖南师范大学自然科学学报》 CAS 北大核心 2005年第4期59-62,共4页 Journal of Natural Science of Hunan Normal University
基金 湖南省教育厅重点课题资助项目(03A026)
关键词 苯并咪唑 铕配合物 DNA键合 benzimidazole Europium(Ⅲ) complex DNA-binding
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参考文献14

  • 1杨频,宋宇飞.金属配合物键合DNA的研究进展[J].化学进展,2000,12(1):32-40. 被引量:29
  • 2O'DONOGHUE K A, KELLY J M, KRUGER P E. Unusual photophysical switching in a Ru(Ⅱ) diimine DNA probe caused by amide functionalisation[J]. Dalton Trans, 2004, ( 1 ) : 13-15.
  • 3HOSSAIN M D, UENO R, HAGA M. Synthesis and tuning of chemical properties by protonation/deprotonation of novel dinuclear ruthenium complexes containing 2,6,2', 6'- tetra( 4,5-dimethylbenzimidazol-2-yl )-4,4' -bipyridine [J].Inorg Chem Conma, 2000, ( 3 ) : 35-38.
  • 4郭茂林,杨频.金属有机配合物对DNA的断链作用[J].高等学校化学学报,1995,16(7):1014-1015. 被引量:8
  • 5白银娟,路军,史真,马怀让.五元氮杂环的开环反应研究进展[J].有机化学,2001,21(9):648-654. 被引量:4
  • 6RAJAN R, RAJARAM R, NAIR B U, et al. Synthesis, characterisation and superoxide dismutase activity of a manganese(Ⅱ) complex[J].J Chem Soc Dalton Trans, 1996:2019-2021.
  • 7VAIDYANATHAN G V, BALACHANDRAN U N. Photooxidation of DNA by a cobalt ( Ⅱ ) tridentate complex [ J ]. J Inorg Biochem,2003, 94: 121-126.
  • 8VAIDYANATHAN G V, BA[ACHANDRAN U N. Synthesis, characterization and DNA binding studies of a ruthenimu(Ⅱ) complex[J].J Inorg Biochem, 2002, 91 : 405-412.
  • 9WANG J L, SHUAI L, XIAO X M. Synthesis, characterization and DNA binding stuches of a zinc complex with 2,6-his( lxmzimidazol-2-yl) pyridine[J]. J Inorganic Biochem, 2005, 99(3) : 883-885.
  • 10谭年元,肖小明,王娇亮,松村竹子.新型多吡啶钴(Ⅲ)配合物的合成、表征及与DNA作用的光谱研究[J].湖南师范大学自然科学学报,2003,26(3):56-59. 被引量:4

二级参考文献50

  • 1杨频,郭茂林,杨斌盛.二氯二茂钛与DNA作用的研究[J].科学通报,1993,38(22):2049-2052. 被引量:12
  • 2HIORT C LINCOLN P NORDéN B.DNA-binding of Δ- and Λ-[Ru(phen)2DPPZ]2+[J].J Am Chem Soc,1993,115:3-3.
  • 3FRIEDMAN A E,CHAMBRON J C,SAUVAGE J P,et al. Molecular “light switch” for DNA: [Ru(bpy)2-(dppz) ]^2+ [J]. J Am Chem Soe, 1990,112:4960.
  • 4JIN Lan,YANG Pin. Symhesis and DNA binding studies of Co^Ⅲ mixed-ligand complex oontaining dipyrido[3,2-a; 2′,3′-c]phenazine and phen[J]. Polyhedron, 1997,16:3395.
  • 5HIORT C, LINCOLN P, NORIMN B. DNA-binding of △- and △- [ Ru(phen)2 DPPZ]^2+ [ J]. J Am Chem Soc, 1993,115: 3 448.
  • 6GRASSINI S G,ISOLA S. Thin-layer chromatrogr-aphie detection of some impurities in cobalt( Ⅲ ) complexes[J]. J Chromatogr, 1978,154:127.
  • 7HAMMEIT L P, WALDEN G H, EDMONDS S M. New indicators for oxidimetry: some phenanthroline and diphenylamine derivatives[J]. J Am Chem Soc,1934,56:1093.
  • 8DICKESON J E,SUMMERS L A. Divatives of 1.10-phen-artthroline-5,6-quimne[J]. Aunt J Chem, 1970,23:1023.
  • 9JERRY F O,JA1VIES T A,CHABLES K M. Preparation of high purity acetonitrile[J]. Anal Chem, 1965,37:1161.
  • 10REICHMA.NN M E,RICE S A,THOMAS C A, et al. A further examination of the molecular weight and size of desoxy-pentose nucleic acid[J]. J Am Chem Soc, 1954,76:3047.

共引文献55

同被引文献15

  • 1肖小明,王姣亮,周燕霞,谭年元,帅丽.微波辐射下2,6-二(苯并咪唑-2′)吡啶的合成[J].湖南师范大学自然科学学报,2005,28(1):44-47. 被引量:15
  • 2沈文馨,苏亚勤,刘永林,李翔.XRF/EDTA滴定法测定钐铕钆富集物样品稀土总量[J].分析科学学报,2005,21(3):343-344. 被引量:5
  • 3Vaidyanathan G V,Balachandran U N.Photooxidation of DNA by a Cobalt(Ⅰ)Tridentate Complex[J].J.Inorg.Biochem.,2003.94(1-2):121-126.
  • 4Vaidyanathan G V,Balachandran U N.Synthesis,Characterization and DNA Binding Studies of a Ruthenium(Ⅰ)Complex[J].J.Inorg.Bioehem.,2002,91(2):405-412.
  • 5Wang J L,Shuai L,Xiao X M.Synthesis,Characterization and DNA Binding Studies of a Zinc Complex with 2,6-Bis(Benzimidazol-2-yl)Pyridine[J].Journal of Inorganw Biochemistry,2005,99(3):883-885.
  • 6Zhang S C,Zhu Y G,Tu C et al.A Novel Cytotoxie Ternary Copper(Ⅱ)Complex of 1,10-Phenanthroline and Lthreonine with DNA Nuclease Activity[J].J.Inorg.Biochem.,2004,98(12):2099-2106.
  • 7Mariappan M,Maiya B G.Effects of Anthracene and Pyrene Units on the Interactions of Novel Polypyridylruthenium(Ⅰ)Mixed-Ligand Complexes with DNA[J].J.Inorg.Chem.,2005,(11):2164-2173.
  • 8Cater M T,Rodriguez M,Bard A J.Voltammetric Studies of the Interaction of Metal Chelats with.DNA.2.Tris-Chelated Complexes of Tris-Chehted Complexes of Cobalt(Ⅱ)and Iron(Ⅰ)with 1,10-Phenanthroline and 2,2'-Bipyridine[J].J.Am.Chem.Soc.,1989,111(24):8901-8911.
  • 9Alan Wolfe,George H,Shimer,Jr.Thomas Meehan.Polycyclic Aromatic Hydrocarbons Physically Intereahte Into Duplex Regions of Denatured DNA[J].Biochem.,1987,26(20):6392-6396.
  • 10Cory M.Mckee D D,Kagan J et al.Design,Synthesis,and DNA Binding Properties of Bifunctional Intercalators.Comparison of Polymethylene and Diphenyl Ether Chains Connecting Phenanthridine[J].J.Am.Chem.Soc.,1985,107(8):2528-2536.

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