大肠癌的肿瘤坏死因子和白细胞介素-1基因多态性研究
被引量：1
摘要
大肠癌是常见的消化道恶性肿瘤之一,其发病机制仍不清楚.目前免疫遗传素质与大肠癌的关系越来越受到重视,肿瘤坏死因子(TNF)和白细胞介素-1(IL-1)是体内具有多种生物活性的重要细胞因子,有抗肿瘤、抗病毒感染及免疫调节作用.因此,本文对浙江地区汉族人群TNF-α和IL-1基因多态性分布进行研究,并分析其与大肠癌的相关性,阐明TNF-α和IL-1基因多态性在大肠癌发病中的作用.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2005年第11期681-682,共2页
Chinese Journal of Digestion
基金
浙江省卫生厅科研基金(97420)
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