摘要
Objective： To explore mechanisms of acupuncture for the treatment of obesity complicated with prernenstrual tension syndrome （PTS）. Methods： By means of syndrome-differentiation, 45 female simple obese （SO） patients with PTS （SO＋ PTS group and 35 simple obesity patients （SO group） were treated with body acupuncture combined with ear acupuncture. Thirtythree normal women subjects were assigned to control group. Changes in symptoms, signs, obesity index, clinical indices of disease and syndrome, equilibrium index of the vegetative nervous system （Y value）, blood estradiol （E2）, progesterone （P）, aldosterone （Aid） and lipid levels were detected and compared before and after the treatment. Results： Before acupuncture treatmerit, the obesity index, clinical indices of disease and syndrome, Y value, E2/P ratio and Aid in these patients were obviously increased, and E2 and P levels decreased. After the treatment, the body weight of the patients was reduced, and the increased obesity index, clinical indices of diseases and syndromes, Y value, E2/P ratio and Aid were markedly lowered （P〈0.05, or P 〈 0.01）, and the decreased E2 and P levels elevated significantly （P〈 0.01）. Conclusion： Acupuncture exerts favorable regulative function on clinical indices of disease and syndrome, Y value, E2, P, Aid, lipid and E2/P in obese patients with PTS, which may be related to its resultant improvement of the functions of the hypothalamo-pituitary-gonedal axis, hypothalamo-pituitary-adrenal axis and the vegetative nervous system.
Objective: To explore mechanisms of acupuncture for the treatment of obesity complicated with premenstrual tension syndrome （PTS）. Methods: By means of syndrome-differentiation, 45 female simple obese （SO） patients with PTS (SO+PTS group and 35 simple obesity patients （SO group） were treated with body acupuncture combined with ear acupuncture. Thirty-three normal women subjects were assigned to control group. Changes in symptoms, signs, obesity index, clinical indices of disease and syndrome, equilibrium index of the vegetative nervous system （Y value）, blood estradiol （E2）, progesterone （P）, aldosterone （Ald） and lipid levels were detected and compared before and after the treatment. Results: Before acupuncture treatment, the obesity index, clinical indices of disease and syndrome, Y value, E2/P ratio and Ald in these patients were obviously increased, and E2 and P levels decreased. After the treatment, the body weight of the patients was reduced, and the increased obesity index, clinical indices of diseases and syndromes, Y value, E2/P ratio and Ald were markedly lowered （P<0.05, or P<0.01）, and the decreased E2 and P levels elevated significantly （P<0.01）. Conclusion: Acupuncture exerts favorable regulative function on clinical indices of disease and syndrome, Y value, E2, P, Ald, lipid and E2/P in obese patients with PTS, which may be related to its resultant improvement of the functions of the hypothalamo-pituitary-gonadal axis, hypothalamo-pituitary-adrenal axis and the vegetative nervous system.
