唾液腺上皮性肿瘤1209例临床分析

Clinical analysis of 1209 cases with epithelial tumors in the salivary glands

目的:了解1990～2005年间唾液腺上皮性肿瘤的临床流行病学特点。方法:对南京大学医学院附属口腔医院1990年2月至2005年2月15年间收治的1209例唾液腺上皮性肿瘤患者进行回顾研究,对其病理类型、好发部位、年龄和性别等进行统计分析。结果:1209例患者中,良性肿瘤与恶性肿瘤之比为1.96∶1,男女之比为1∶1。良性肿瘤以多形性腺瘤最多见(76.75%),其次为Warthin瘤(14.75%);恶性肿瘤以黏液表皮样癌最常见(34.2%),其次为腺样囊性癌(26.2%)。良性肿瘤和恶性肿瘤的好发部位相同,均以腮腺最多,腭部小唾液腺和下颌下腺分列第2位和第3位;发病年龄主要集中于20～70岁之间。结论:唾液腺上皮性肿瘤可发生于任何年龄,良性多于恶性,多形性腺瘤是其最常见的病理类型。

PURPOSE： To analyse the clinical epidemiologic features of epithelial tumors of the salivary glands from 1990 to 2005. METHODS： 1209 cases of epithelial tumors of salivary glands who were treated at the Affiliated Stomatologieal Hospital, Medical College of Nanjing University from 1990 to 2005 were retrospectively studied. The pathological types and distributions of location, age and sex of them were analysed. RESULTS： In 1209 cases, the ratio of benign to malignant tumors was 1.96：1, and that of male to female was nearly 1：1. The most common type of benign tumors was pleomorphic adenoma, followed by Warthin＇s tumor. Accordingly, the most common malignant tumor was mueoepidermoid carcinoma, followed by adenoid cystic carcinoma. As to the location, benign and malignant tumors were alike. They developed mostly in the parotid gland, followed by the palatal minor salivary gland and the submandibular gland. The age of the patients was mostly concentrated between 20 and 70 years old. CONCLUSIONS： Epithelial tumors of the salivary glands can occur in any ages. The morbility of benign tumor is more than that of malignant one. The most common type of epithelial tumors of salivary glands is still pleomorphic adenoma.